PMID: 6068Jan 1, 1976

Partial purification and study of gamma-glutamyl transpeptidase from sheep cerebral capillaries

Biochimie
M Grandgeorge, P Morelis

Abstract

Gamma-glutamyl transpeptidase was purified 53 times from Sheep brain cortex capillaries. On gel filtration it appears homogeneous with a M.W. = 350 000. The enzyme is likely a glycoprotein, the properties of which are close to hog kidney gamma-glutamyl transpeptidase ; gamma-glutamyl aminoacid formation is assayed electrophoretically. The results obtained using several aminoacids are in favour of the existence of different units, specific of each group of aminoacids ; together with the data from structural analogs, they support the hypothesis that gamma-glutamyl transpeptidase participates in aminoacid transport accross blood brain barrier.

Citations

Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo

Jul 1, 1985·Neurochemical Research·E KvammeG Svenneby

Solubilization and some properties of gamma-glutamyltransferase from human brain microvessels

Jul 1, 1984·Neurochemical Research·J Veselý, M Cernoch

Studies of gamma-glutamyltransferase activity in the brain tissue post mortem

Jul 1, 1984·Neurochemical Research·J Veselý, M Cernoch

Gamma Glutamyl Transferase in domestic animals

Mar 1, 1983·Veterinary Research Communications·J P BraunA G Rico

Regional distribution of membrane-bound gamma-glutamyl transpeptidase activity in mouse brain. Comparison with rabbit brain

Dec 1, 1979·Neurochemical Research·V LisýZ Lodin

Changes of cerebral gamma glutamyltransferase activities after treatment with exogenous inducers

Apr 1, 1987·Neurochemical Research·J F Ghersi-EgeaG Siest

Isolation and purification of multiple forms of gamma-glutamyl transpeptidase from rat brain

Feb 1, 1980·Neurochemical Research·E Reyes, T D Barela

Partial purification of gamma-glutamyltransferase from human brain microvessels

Oct 1, 1985·Neurochemical Research·J VeselýM Cernoch

Properties of γ-glutamyltransferase in developing rat brain

Jan 1, 1984·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M Pajari

Related Concepts

Metazoa
Blood - Brain Barrier Anatomy
Blood Capillaries
Insula of Reil
Gamma-glutamyl transferase
Dall Sheep
PMS-Tryptophan

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