Partial Resurfacing of the Knee with the BioPoly Implant: Interim Report at 2 Years

JB & JS Open Access
Dinesh NathwaniVladimir Bobić

Abstract

Current treatments for focal chondral and osteochondral lesions of the femoral condyle have been associated with variable outcomes. We conducted a clinical trial of the BioPoly RS Partial Resurfacing Knee Implant to address this unmet need. We performed a single-arm, prospective study in which 33 patients with focal cartilage lesions affecting the femoral condyle were managed with the BioPoly RS Partial Resurfacing Knee Implant. Knee injury and Osteoarthritis Outcome Score (KOOS) scores, a visual analog scale (VAS) for pain, the Short Form-36 (SF-36) physical component score , and the Tegner activity score were used to assess outcomes preoperatively and at 6 months, 1 year, and 2 years postoperatively. The KOOS outcomes at 2 years were compared with historical outcomes following microfracture treatment. We found significant and clinically meaningful improvements in the KOOS scores, VAS pain score, and SF-36 physical component score (p < 0.025) when the values at all 3 postoperative time points were compared with the preoperative scores, and we also found significant improvements when the Tegner activity score at 2 years was compared with the preoperative score (p < 0.025). More than half of the cohort of patients had had a prev...Continue Reading

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Citations

Jul 3, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ralph M JeukenPieter J Emans
Sep 18, 2020·Advanced Healthcare Materials·Jiacheng ZhaoBenjamin J Wiley
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Jan 19, 2021·ACS Biomaterials Science & Engineering·Michael T Frassica, Melissa A Grunlan
Apr 23, 2019·Biomacromolecules·A Kristen MeansMelissa A Grunlan

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