Aug 1, 1989

Partial transection of the ipsilateral cervical spinal cord evokes a sustained increase in the adrenal section of catecholamines in the cat

Journal of the Autonomic Nervous System
D A Bereiter

Abstract

The importance of cervical spinal pathways on the adrenal secretion of catecholamines was assessed in chloralose-anesthetized cats. Partial transections of the upper cervical spinal cord were made ipsilateral (n = 21) or contralateral (n = 10) to the adrenal vein sampling catheter. Ipsilateral cuts evoked an immediate increase in the adrenal secretion of epinephrine that remained elevated at 60 min (+89.7 +/- 27.0 ng/min, P less than 0.001) and increased the epinephrine/norepinephrine secretory ratio from 1.99 +/- 0.4 to 5.02 +/- 0.6 by 60 min (P less than 0.01) indicating a preferential augmentation of the secretion of epinephrine. The magnitude of the increase in secretion of epinephrine was well correlated with the cross-sectional area of the ipsilateral cut (rs = 0.681, P less than 0.01). In contrast, partial transections of similar size made contralateral to the adrenal vein sample evoked significantly smaller increases in the adrenal secretion of epinephrine by 60 min (+12.7 +/- 4.8 ng/min) and were not correlated with the cross-sectional area of the cut. The region of transection common to those experiments that caused the greatest increase in the secretion of catecholamines included the deep laminae (laminae V-VII) with...Continue Reading

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Citations

Mentioned in this Paper

Arterial Pulse Pressure
Biochemical Pathway
Central Gray Substance
Catecholamines Measurement
Neurosecretory Systems
Entire Upper Cervical Spinal Cord
Lamiinae (invertebrate)
Process of Secretion
Entire Cervical Spinal Cord
Structure of Upper Cervical Spinal Cord

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