Participant satisfaction with clinical trial experience and post-trial transitioning to HIV care in Kenya

International Journal of STD & AIDS
Isdora OderoDeborah A Gust

Abstract

We conducted an exploratory analysis of former HIV Prevention Trials Network 052 (HPTN 052) clinical trial participants in 2016 to assess their (1) satisfaction with the HPTN 052 clinical trial care and treatment, and reasons for joining the trial; and (2) perspectives about the post-trial transition to public HIV care centers. Quantitative data showed that, of the 70 survey participants, 94.3% (n = 66) reported being very satisfied with the care and treatment they received while participating in the clinical trial and 51.4% (n = 36) reported they joined the study because they would receive information to improve their own or their partner's health. Qualitative data (five in-depth interviews and two focus group discussions) analysis revealed the following themes: transition experiences; perceived superior clinical trial care; study benefits not offered at public HIV care centers; and the public HIV care centers' indifference to the uninfected partner. For some HPTN 052 participants, transition to HIV care clinics was disappointing. Clinical trial investigators and local Institutional Review Boards should consider the need for safeguards and oversight of post-trial health care for trial participants after the trial ends, especia...Continue Reading

Associated Clinical Trials

References

Dec 3, 1998·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·F W VerheggenG J Kok
Feb 21, 2004·The Journal of Infectious Diseases·Ezekiel J EmanuelChristine Grady
Nov 30, 2007·PLoS Medicine·Gail E HendersonCatherine R Zimmer
Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Jul 7, 2012·JRSM Short Reports·Zafar AhmadNeil Rushton
Feb 15, 2014·American Journal of Public Health·Jenny A HigginsJohn S Santelli
Jan 9, 2016·British Journal of Clinical Pharmacology·Rafael Dal-RéDavid Wendler
Oct 8, 2016·Trials·Bethann Mangel PflugeisenPaul J Amoroso
Mar 1, 2018·Journal of Medical Ethics·Amy PaulJeremy Sugarman
Apr 21, 2018·Lancet·Hae Lin ChoChristine Grady

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Citations

Sep 10, 2020·Children and Youth Services Review·A P Simons-RudolphW K Luseno

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