PMID: 8974209Dec 1, 1996Paper

Participants' perceptions of a phase I colon cancer chemoprevention trial

Controlled Clinical Trials
K S HudmonR J Winn

Abstract

To assess participants' perceptions of a phase I colon cancer chemoprevention trial using a calcium intervention, questionnaires were mailed to trial participants at the conclusion of the study. Responses to questionnaire items reported here include (1) perceived benefits and barriers of participation, (2) interest in participating in future trials, (3) willingness to pay trial expenses out of pocket, and (4) posttrial continuation of the calcium regimen. The study found that the most highly rated trial benefit was the perception of potential colon cancer prevention; the trial barrier reported to be the most troublesome was inappropriate or mistaken billing for study visits. Three fourths of the subjects expressed an interest in future trials of the same duration. For trials of longer duration, this percentage decreased to 66%. Approximately half did not object to participation in future trials involving placebos, and just over one third indicated that they would either definitely (8%) or probably (27%) have joined the calcium trial even if they had to pay some study expenses out of pocket. Over 90% indicated they would continue taking the calcium pills if calcium is shown to be effective. The level of perceived benefits was po...Continue Reading

References

Jan 1, 1991·Preventive Medicine·D L DeMetsP Carey
Jun 1, 1989·Journal of Behavioral Medicine·M BerensonJ DeCosse
Jun 1, 1985·Controlled Clinical Trials·M E MattsonR McArdle

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Citations

Mar 29, 2001·Journal of Surgical Oncology·P M SimpsonJ S Spratt
May 2, 2000·Critical Reviews in Oncology/hematology·K KrishnanD E Brenner
Sep 13, 2006·The Journal of Cardiovascular Nursing·Joyce C KellenUNKNOWN AFFIRM Investigators and Coordinators
Jan 22, 2005·Journal of Evaluation in Clinical Practice·David A StoneTed J Kaptchuk
Jun 6, 2003·European Journal of Cancer Care·K Cox, J McGarry

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