Participation in an ambulatory e-pharmacovigilance system

Pharmacoepidemiology and Drug Safety
Jennifer S HaasDavid W Bates

Abstract

There is growing concern about whether passive surveillance can detect adverse drug events (ADEs). Our objective was to demonstrate the reach of an interactive voice response system (IVRS) to systematically monitor symptoms experienced by ambulatory patients prescribed one of 31 medications, and to document whether there were differences in our ability to contact certain populations. Patients receiving a prescription for a target medication at one of 11 clinics were eligible for a cross-sectional IVRS survey, "e-pharmacovigilance," with a follow-up survey done 3 months later if the target medication was still listed on the patient's active medication list. 902 patients participated, representing 43.3% of contacted and 25.7% of potentially eligible patients with a working phone. After adjustment for demographics and drug class, patients >66 years were more likely to participate than those 56-65 years (odds ratio 1.47; 95% confidence interval 1.19-1.81). Hispanics were less likely than whites (0.56; 0.42-0.76), and those in low-income communities less likely to participate than those in high-income communities (0.69; 0.58-0.82). Patients prescribed asthma, or seizure medications were more likely to participate than those prescrib...Continue Reading

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Citations

Apr 20, 2013·American Journal of Public Health·Bridget GaglioRussell E Glasgow
Jul 7, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jennifer S HaasDavid W Bates
Dec 16, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Gordon D Schiff
Jun 14, 2013·Journal of Diabetes Science and Technology·Courtney R LylesUrmimala Sarkar
Jan 17, 2019·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Abhyuday JagannathaHong Yu
Jun 8, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Hisham AljadheyMichael D Murray
Oct 7, 2018·Journal of General Internal Medicine·Gordon D SchiffJennifer S Haas
Mar 13, 2014·Journal of General Internal Medicine·Eta S BernerGordon D Schiff
Jun 25, 2016·Translational Behavioral Medicine·Christine S RitchieJulie L Locher
Sep 22, 2021·BMJ Open Quality·Anjana E SharmaUrmimala Sarkar

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