Get paper from

journal cover

Partitioning heritability by functional annotation using genome-wide association summary statistics

Nature Genetics

Nov 1, 2015

Hilary Kiyo FinucaneAlkes L. Price

Get paper from

Abstract

Recent work has demonstrated that some functional categories of the genome contribute disproportionately to the heritability of complex diseases. Here we analyze a broad set of functional elements, including cell type-specific elements, to estimate their polygenic contributions to herit...read more

Mentioned in this Paper

Biological Markers
Body Mass Index Procedure
Genome
Histone H7
Immune System Diseases
Menarche
Methylation
Genetic Predisposition to Disease
Cell Type
Genetic Equilibrium
83
693
1
Paper Details
References
    • References42
    • Citations87
    • References42
    • Citations87
  • Partitioning heritability by functional annotation using genome-wide association summary statistics

    Nature Genetics

    Nov 1, 2015

    Hilary Kiyo FinucaneAlkes L. Price

    PMID: 26414678

    DOI: 10.1038/ng.3404

    Abstract

    Recent work has demonstrated that some functional categories of the genome contribute disproportionately to the heritability of complex diseases. Here we analyze a broad set of functional elements, including cell type-specific elements, to estimate their polygenic contributions to herit...read more

    Mentioned in this Paper

    Biological Markers
    Body Mass Index Procedure
    Genome
    Histone H7
    Immune System Diseases
    83
    693
    1

    Related Papers

    Paper Details
    References
    • References42
    • Citations87
    • References42
    • Citations87
  • Get paper from

    © 2019 Meta ULC. All rights reserved.

    Hi! We use cookies on this site for analytics purposes. Visit our cookie policy to learn more. By continuing to use our services or closing this banner, you consent to our use of cookies.

    /papers/partitioning-heritability-by-functional/26414678