Partner status and survival after cancer: A competing risks analysis

Cancer Epidemiology
Paramita DasguptaPeter D Baade

Abstract

The survival benefits of having a partner for all cancers combined is well recognized, however its prognostic importance for individual cancer types, including competing mortality causes, is less clear. This study was undertaken to quantify the impact of partner status on survival due to cancer-specific and competing mortality causes. Data were obtained from the population-based Queensland Cancer Registry on 176,050 incident cases of ten leading cancers diagnosed in Queensland (Australia) from 1996 to 2012. Flexible parametric competing-risks models were used to estimate cause-specific hazards and cumulative probabilities of death, adjusting for age, stage (breast, colorectal and melanoma only) and stratifying by sex. Both unpartnered males and females had higher total cumulative probability of death than their partnered counterparts for each site. For example, the survival disadvantage for unpartnered males ranged from 3% to 30% with higher mortality burden from both the primary cancer and competing mortality causes. The cause-specific age-adjusted hazard ratios were also consistent with patients without a partner having increased mortality risk although the specific effect varied by site, sex and cause of death. For all combi...Continue Reading

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Citations

Nov 14, 2019·International Journal of Cancer. Journal International Du Cancer·Zimu WuPierre-Antoine Dugué
Jan 8, 2020·International Journal of Environmental Research and Public Health·Hye-Eun LeeIchiro Kawachi
Jun 8, 2021·Frontiers in Psychology·Bahar NalbantTanja Zimmermann

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