PMID: 3744563DOI: 10.1128/iai.53.3.713-714.1986Sep 1, 1986Paper
Passive immunization of hamsters against experimental infection with the Lyme disease spirochete.
Infection and Immunity
R C JohnsonM Russell
Abstract
Hamsters passively immunized with as little as 0.0125 ml of immune rabbit serum (indirect fluorescent-antibody titer, 1:8,192) were protected from challenge with 1,000 50% infective doses of Borrelia burgdorferi. Cross-protection studies with Minnesota and Connecticut isolates of B. burgdorferi indicated no major differences in their capacity to elicit mutually protective antibodies in rabbits.
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