PMID: 1191515Jun 1, 1975Paper

Passive serum sickness in the mouse: effect of interstrain differences on glomerular deposition of immune complexes.

British Journal of Experimental Pathology
P M Ford

Abstract

Glomerular uptake of passively administered immune complexes in mice differs in different inbred strains. The amount of immune material deposited in the glomeruli in the strains examined is inversely related to the susceptibility to immune complex induced anaphylaxis. The significance of these findings is discussed.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.