Passive transfer of maternal Mycoplasma hyopneumoniae-specific cellular immunity to piglets

Clinical and Vaccine Immunology : CVI
M BandrickThomas Molitor

Abstract

Immunity in the neonatal animal is primarily maternally derived, either by lymphocytes that pass into the newborn across the placenta or following colostrum ingestion. However, the effect of this passively transferred cellular maternal immunity on the newborn's immune repertoire is not clearly understood. Various studies have shown that colostral lymphocytes are activated and possess functional abilities; however, no studies have shown the transfer of colostral antigen-specific T-cell-specific responses in a newborn. In this study we examined the transfer of vaccine-induced Mycoplasma hyopneumoniae cellular immunity from immune dams to newborn piglets. Newborn piglets from vaccinated and nonvaccinated dams were assessed in two ways for cellular immune responses specific to M. hyopneumoniae: (i) delayed-type hypersensitivity (DTH) testing and (ii) in vitro lymphocyte proliferation, assayed on piglet blood lymphocytes and sow colostral lymphocytes. DTH responses to M. hyopneumoniae were detected only for offspring of vaccinated sows, whereas DTH responses to the nonspecific mitogen phytohemagglutinin were seen for all piglets. M. hyopneumoniae-specific proliferation was seen for colostral lymphocytes from vaccinated sows and for ...Continue Reading

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Citations

Dec 24, 2009·BMC Veterinary Research·Esther SteinerKenneth McCullough
Jan 18, 2013·PloS One·Kyle M SchachtschneiderMaria Pieters
Jan 5, 2014·Developmental and Comparative Immunology·Benoît LevastHenri Salmon
Jun 16, 2012·Veterinary Immunology and Immunopathology·J SchmiedB Wilkie
Apr 29, 2011·Veterinary Immunology and Immunopathology·Katerina NechvatalovaMartin Faldyna
Mar 19, 2016·Animal Science Journal = Nihon Chikusan Gakkaihō·Shohei OgawaRyo Inoue
Sep 2, 2014·Veterinary Immunology and Immunopathology·Gillian A PerkinsBettina Wagner
Nov 21, 2013·Developmental and Comparative Immunology·Meggan BandrickThomas W Molitor
Mar 1, 2016·Journal of Dairy Science·S N LangelI Kanevsky-Mullarky
Dec 23, 2011·Vaccine·Douglas C Hodgins, Patricia E Shewen
Jul 6, 2014·Veterinary Microbiology·Maria PietersAaron K Rendahl
Sep 1, 2016·American Journal of Veterinary Research·Shohei OgawaRyo Inoue
Sep 23, 2016·Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·Jelena Kecman, Martin Wähner
Feb 2, 2017·Animal Science Journal = Nihon Chikusan Gakkaihō·Toshio SatoTakamitsu Tsukahara
Aug 24, 2017·Transboundary and Emerging Diseases·D MaesM Pieters
Oct 13, 2012·The Journal of Veterinary Medical Science·Hwi Won SeoChanhee Chae
Mar 7, 2021·Animals : an Open Access Journal From MDPI·Xiaojun ZhangZhaohui Chen
Jul 2, 2021·Veterinary Research·Evelien BiebautDominiek Maes
Aug 20, 2021·Animal Science Journal = Nihon Chikusan Gakkaihō·Ryo Inoue, Takamitsu Tsukahara

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