Past and Present of Total Artificial Heart Therapy: A Success Story

Medical Science Monitor Basic Research
Mostafa SamakAlexander Weymann

Abstract

The totally artificial heart (TAH) is among the most prominent medical innovations of the 21st century, especially due to the increasing population with end-stage heart failure. The progressive course of the disease, its resistance to conventional therapy, and the scarcity of hearts available for transplantation were the prime impetus for developing a TAH, especially when other options of mechanical circulatory assist devices are exhausted. In this review, we narrate the history of TAH, give an overview of its technology, and address the pros and cons of the currently available TAH models in light of published clinical experience.

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Citations

Feb 19, 2016·Medical Science Monitor Basic Research·Antonia SchulzHolger Hotz
Nov 1, 2015·Perfusion·Prashant N MohiteAndré R Simon
Jul 26, 2018·Artificial Organs·Doris A TaylorLuiz C Sampaio
May 18, 2016·The International Journal of Artificial Organs·Mohamed ZeriouhAchim Koch
Jul 2, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Kaiyun GuYi Zeng
May 24, 2019·Current Medicinal Chemistry·Alexandros BriasoulisRabea Asleh
Oct 2, 2020·Artificial Organs·Mario DiedrichSebastian Jansen

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Software Mentioned

CardioWest
Abiocor
Freedom
AbioScore
SynCardia
HeartWare

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