Past, present and future of kidney paired donation transplantation in India

World Journal of Transplantation
Vivek B KuteHargovind L Trivedi

Abstract

One third of healthy willing living kidney donors are rejected due to ABO blood group incompatibility and donor specific antibody. This increases pre-transplant dialysis duration leading to increased morbidity and mortality on the kidney transplantation waiting list. Over the last decade kidney paired donation is most rapidly increased source of living kidney donors. In a kidney transplantation program dominated by living donor kidney transplantation, kidney paired donation is a legal and valid alternative strategy to increase living donor kidney transplantation. This is more useful in countries with limited resources where ABO incompatible kidney transplantation or desensitization protocol is not feasible because of costs/infectious complications and deceased donor kidney transplantation is in initial stages. The matching allocation, ABO blood type imbalance, reciprocity, simultaneity, geography were the limitation for the expansion of kidney paired donation. Here we describe different successful ways to increase living donor kidney transplantation through kidney paired donation. Compatible pairs, domino chain, combination of kidney paired donation with desensitization or ABO incompatible transplantation, international kidney ...Continue Reading

Citations

Aug 24, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Francis L Delmonico, Nancy L Ascher
Jun 26, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Robert ÖllingerJohann Pratschke
Jul 11, 2018·World Journal of Transplantation·Vivek B KutePranjal R Modi

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