Pasture flock chicken cecal microbiome responses to prebiotics and plum fiber feed amendments

Poultry Science
S H ParkS C Ricke


When prebiotics and other fermentation substrates are delivered to animals as feed supplements, the typical goal is to improve weight gain and feed conversion. In this work, we examined pasture flock chicken cecal contents using next generation sequencing (NGS) to identify and understand the composition of the microbiome when prebiotics and fermentation substrates were supplemented. We generated 16S rRNA sequencing data for 120 separate cecal samples from groups of chickens receiving one of 3 prebiotics or fiber feed additives. The data indicated that respective feed additives enrich for specific bacterial community members and modulate the diversity of the microbiome. We applied synthetic learning in microbial ecology (SLiME) analysis to interpret 16S rRNA microbial community data and identify specific bacterial operational taxonomic units (OTU) that are predictive of the particular feed additives used in these experiments. The results suggest that feed can influence microbiome composition in a predictable way, and thus diet may have indirect effects on weight gain and feed conversion through the microbiome.


Aug 1, 1991·Biochemical Society Transactions·H Hidaka, M Hirayama
Jul 1, 1989·Applied and Environmental Microbiology·Gerald W TannockS D Feighner
Feb 1, 1988·Applied and Environmental Microbiology·S D Feighner, M P Dashkevicz
May 1, 1985·The Journal of Nutrition·A Krogdahl
Jun 1, 1995·The Journal of Nutrition·G R Gibson, M B Roberfroid
Aug 1, 1996·The British Journal of Nutrition·M S AllesJ B Jansen
Apr 5, 2003·Applied and Environmental Microbiology·Handan Kaplan, Robert W Hutkins
Apr 25, 2003·Poultry Science·J A Patterson, K M Burkholder
Nov 7, 2003·Applied and Environmental Microbiology·Jiangrang LuMargie D Lee
Apr 19, 2006·Avian Diseases·A Singh DhillonD Bandli
Jul 26, 2006·Critical Reviews in Food Science and Nutrition·Katrien SwennenJan A Delcour
Aug 22, 2006·Alimentary Pharmacology & Therapeutics·S MacfarlaneJ H Cummings
Nov 7, 2006·Applied and Environmental Microbiology·Suwat SaengkerdsubS C Ricke
Dec 22, 2006·Nature·Ruth E LeyJeffrey I Gordon
Oct 14, 2008·Anaerobe·S M HorrocksS C Ricke
Dec 24, 2008·Animal Health Research Reviews·T R CallawayD J Nisbet
Nov 28, 2009·Applied Microbiology and Biotechnology·Ah-Reum Park, Deok-Kun Oh
Apr 13, 2010·The Veterinary Journal·Gerard HuyghebaertFilip Van Immerseel
Apr 13, 2010·International Journal of Food Microbiology·Francesca GaggìaBruno Biavati
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Aug 6, 2010·The ISME Journal·Alan W WalkerHarry J Flint
Jan 18, 2012·Applied Microbiology and Biotechnology·Dragana StanleyRobert J Moore
Feb 22, 2013·Critical Reviews in Microbiology·Suwat Saengkerdsub, S C Ricke
Aug 27, 2013·Applied and Environmental Microbiology·Sarah P PreheimEric J Alm


Nov 15, 2018·Frontiers in Veterinary Science·Po-Yun Teng, Woo Kyun Kim
Jun 11, 2019·Frontiers in Veterinary Science·Zhaohao ShiS C Ricke
Mar 29, 2019·MSphere·Milton ThomasJoy Scaria
Jun 9, 2021·Poultry Science·S C Ricke

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.