Abstract
Distinguishing weak allergic reactions from irritant patch test reactions may be difficult. To describe the dermoscopic features of allergic reactions (especially weak allergic ones) and irritant patch test reactions, and to assess the suitability of dermoscopy in supporting differential diagnosis. Eligible participants for this observational, cross-sectional study included consecutive adult outpatients patch tested during a 12-month period, who developed any skin reaction. Healthy volunteers were patch tested with sodium lauryl sulfate as irritant controls. At the 72-hour reading, patch test reactions were recorded both with a digital camera and a digital dermoscopic system. For each reaction, clinical and dermoscopic variables were separately assessed, scored, and then compared. Erythema, vessels, and vesiculation were constant dermoscopic features of allergic reactions (n = 173). In 46 weak (+) allergic reactions, dermoscopy showed (a) erythema (100%), (b) dense polymorphic vessels (100%), and (c) whitish vesicles (78.3%). Scores for vesicles and dotted vessels were significantly higher in weak allergic than in irritant reactions. Vesicles were identified as the chief dermoscopic parameter for correctly distinguishing weak a...Continue Reading
References
Aug 1, 1987·Contact Dermatitis·J Serup, B Staberg
Aug 1, 1997·Contact Dermatitis·R A TupkerJ Serup
Mar 19, 2003·Contact Dermatitis·H Löffler, R Happle
Jan 17, 2004·Journal of the American Academy of Dermatology·Kirsty SwindellsSalvador González
Aug 26, 2004·Dermatologic Therapy·Lisa A Garner
Jan 18, 2006·Journal of Biomedical Optics·Thilo GambichlerKlaus Hoffmann
May 19, 2009·European Journal of Dermatology : EJD·Audrey NosbaumJean-François Nicolas
Mar 30, 2011·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Marco ArdigòGiovanni Pellacani
Feb 3, 2012·The British Journal of Dermatology·A LallasI Zalaudek
Oct 1, 2013·Dermatologic Clinics·Aimilios LallasZoe Apalla
Sep 5, 2014·Archives of Dermatological Research·Marc A L M BooneV Del Marmol
Jan 22, 2015·Lasers in Medical Science·D SlodownikC D Enk
Jul 17, 2015·Contact Dermatitis·Jeanne D JohansenWolfgang Uter
Oct 24, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Yul W YangAaron R Mangold
Nov 2, 2018·The British Journal of Dermatology·M CorazzaA Borghi
Mar 20, 2019·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Ali Rajabi-EstarabadiAntonella Tosti