Patented techniques for the extraction and isolation of secoisolari-ciresinol diglucoside from flaxseed

Recent Patents on Food, Nutrition & Agriculture
Farah S Hosseinian, Trust Beta

Abstract

Plant lignans are phenolic compounds generally containing a dibenzylbutane skeleton. Secoisolariciresinol diglucoside (SDG) is the major lignan found in flaxseed. SDG is known to have antioxidant and anticancer properties. SDG can potentially be used as a natural antioxidant in foods thereby preventing further oxidation reactions and thus enhance the shelf life of foods. This article reviews the patents that are concerned with the extraction of SDG from flaxseed, the richest plant source of lignans. Most of the patented techniques for the extraction, isolation, and purification of SDG are conducted on defatted flaxseed and whole flaxseed. Flaxseed hull is potentially a good starting material. Furthermore, most methods use aliphatic alcohols (methanol, ethanol, isopropanol, butanol) to extract the complexed form of SDG. Combinations of these solvents are commonly used with water. Alkaline hydrolysis liberates SDG from its complexed form. SDG is enriched by a process involving either liquid-liquid partitioning or passing the aqueous phase through anion exchange resins or C18 resins. The SDG is recovered after evaporation of the water. Analytical HPLC coupled with mass spectrometry is performed to determine the quantity and purity...Continue Reading

Citations

Jul 29, 2015·Nutrition Journal·Muhammad ImranShahzad Hussain
Mar 1, 2011·Journal of Adolescent and Young Adult Oncology·Shree RajaniSarah M Sharaf
Apr 2, 2015·Journal of Food Science and Technology·Priyanka KajlaDev Raj Sood
Oct 27, 2021·Journal of Natural Products·Yajia GuoMartin J T Reaney

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