PMID: 11924707Apr 2, 2002Paper

Paternity testing after pregnancy termination using laser microdissection of chorionic villi

International Journal of Legal Medicine
Martin BauerDieter Patzelt

Abstract

We report an unusual case of paternity testing from residues of chorionic villi 5 weeks after pregnancy termination. The autopsy of a 32-year-old female homicide victim revealed the presence of intact chorionic villi at the former placenta implantation site. Fetal cells were selectively isolated by laser-induced microdissection of the remaining villi to avoid contamination with maternal DNA. Simultaneous amplification of 12 STR loci in 2 PCR reactions resulted in a combined probability of paternity of 99.94%. This case demonstrates that laser-assisted microdissection and multiplex STR typing provide tools for paternity testing performed on endometrial mucosa long after the product of conception was removed by therapeutic abortion.

Citations

Sep 14, 2002·Prenatal Diagnosis
Oct 14, 2004·Der Pathologe·M A VerhoffF Heidorn
Aug 4, 2010·International Journal of Legal Medicine·Mado Vandewoestyne, Dieter Deforce
Oct 11, 2003·Forensic Science International : Synergy·K ElliottP Gill
May 10, 2003·Journal of Clinical Laser Medicine & Surgery
Dec 9, 2004·Expert Opinion on Therapeutic Targets·D C PritloveM Vatish
Jan 11, 2011·Journal of Forensic and Legal Medicine·Zlatko JakovskiBiljana Janeska
Aug 24, 2010·Forensic Science International : Synergy·Burkhard MadeaFrank Musshoff
May 16, 2006·Journal of Forensic Sciences·Jessica C VoorheesJames P Landers
May 26, 2007·Journal of Forensic Sciences·Jessica V NorrisJames P Landers

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