Path analysis of metabolic syndrome components in black versus white children, adolescents, and adults: the Bogalusa Heart Study

Annals of Epidemiology
Wei ChenG S Berenson

Abstract

Examine the complex relationships among metabolic syndrome components in black and white individuals by growth periods. Path analyses of metabolic syndrome components were performed on 8203 black and white healthy subjects (64.3% white and 47.9% male) comprising children (4-11 years), adolescents (12-18 years), and adults (19-44 years). The direct effect of body mass index (BMI) on fasting insulin levels was greatest among all the paths for each age group in both races. In general, path coefficients were greater in whites than in blacks except for the age-mean arterial pressure (MAP) path and greater in children and adults than in adolescents. The direct age effect on MAP was greater in black versus white adults (p = 0.010 for race difference). Whites showed greater direct effects of BMI on MAP in children (p = 0.007), adolescents (p = 0.090), and adults (p = 0.022); BMI on insulin in adolescents (p < 0.001); BMI on triglycerides in children (p = 0.003); and insulin on triglycerides in adults (p < 0.001). A race difference in the effect of BMI on fasting glucose was noted among adolescents (p = 0.048). The black-white differences in the relationships of obesity and insulin resistance measures to other components may account for...Continue Reading

Associated Clinical Trials

May 26, 2000·Lydia A. Bazzano

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Citations

Sep 29, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·H GaoR M van Dam
Aug 19, 2011·Metabolic Syndrome and Related Disorders·Jason L VassyJames B Meigs
Jul 1, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kevin C OeffingerGloria Lena Vega
Apr 22, 2015·The Journal of Pediatrics·Matthew G BrowningRonald K Evans
Mar 6, 2012·International Journal of Cardiology·Marc N JarczokJulian F Thayer
Jun 3, 2020·Pediatric Gastroenterology, Hepatology & Nutrition·Helen H WangDavid Q-H Wang
Jul 25, 2019·Ciência & saúde coletiva·Ricardo Franklin de Freitas Mussi, Edio Luiz Petróski
Apr 8, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Miaoying YunWei Chen

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