Path model of factors influencing health-related quality of life among older people with knee osteoarthritis

Nursing & Health Sciences
Suparb Aree-UePhichpraorn Youngcharoen


Chronic illness has a significant effect on quality of life, and a critical measure of health outcomes. Correlations between pain, depressive symptoms, fatigue, and physical function and their direct and indirect effects on quality of life were determined among 200 Thai older population with knee osteoarthritis using the Numeric Rating Scale, the Multidimensional Assessment of Fatigue, and the Thai Geriatric Depression Scale-15. Physical function was investigated by using the Timed Up and Go test. Path analysis revealed significant negative direct paths from pain, depressive symptoms, fatigue, and Timed Up and Go test results to quality of life. Pain, fatigue, and the Timed Up and Go test results had indirect effects on quality of life, while depressive symptoms had no indirect effect on quality of life. Increases in pain, depressive symptoms, fatigue, and Timed Up and Go test results were associated with reductions in quality of life. An understanding of the complex relationship among these variables is beneficial for designing an appropriate intervention for improving quality of life among older people with knee osteoarthritis.


Feb 1, 1991·Journal of the American Geriatrics Society·D Podsiadlo, S Richardson
Apr 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
May 31, 2011·Journal of Pain and Symptom Management·Marianne Jensen HjermstadUNKNOWN European Palliative Care Research Collaborative (EPCRC)
Jul 14, 2011·Rheumatology·Gijs F SnijdersUNKNOWN Nijmegen OsteoArthritis Collaboration Study Group
Nov 23, 2013·Modern Rheumatology·Berat Meryem AlkanOzge Ardıçoğlu
Jan 13, 2015·Heart & Lung : the Journal of Critical Care·Samantha ConleyNancy S Redeker
Jan 22, 2015·Orthopaedic Nursing·Jeanne B Jenkins, Thomas P McCoy
Jan 31, 2015·International Journal of Emergency Medicine·Jiraporn Sri-OnShan Woo Liu
Jul 23, 2015·Revista brasileira de reumatologia·Alyne Hevellen FerreiraRegina Cláudia Barbosa da Silva
Feb 13, 2016·Arthritis Care & Research·Alison HodgesMarlene Fransen
Feb 20, 2016·PharmacoEconomics·Milad Karimi, John Brazier
May 22, 2016·Archives of Physical Medicine and Rehabilitation·Susan L MurphyAnna L Kratz
Nov 16, 2016·Open Access Rheumatology : Research and Reviews·Anirudh SharmaRajiv Gandhi
Jun 14, 2017·Aging Clinical and Experimental Research·Hakan NurTiraje Tuncer
Feb 15, 2018·Journal of the American Geriatrics Society·Keiko SugaiYuji Nishiwaki
May 5, 2018·Journal of Nursing Measurement·Basia BelzaXi Zhang

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