Pathogenesis and tissue distribution of avian infectious bronchitis virus isolate IRFIBV32 (793/B serotype) in experimentally infected broiler chickens.

TheScientificWorldJournal
Zahra BoroomandAli Mohammadi

Abstract

Infectious bronchitis (IB) is one of the most important viral diseases of poultry. The aim of this study was to investigate the distribution of avian infectious bronchitis virus isolate IRFIBV32 (793/B serotype) in experimentally infected chicken. Ninety-one-day-old commercial broilers were divided randomly into two groups (seventy in the experimental and twenty in the control group). Chicks in the experimental group were inoculated intranasally with 10(5) ELD50/0.1 mL of the virus at three weeks of age. The samples from various tissues were collected at1, 2, 3, 5, 7, 11, 13, 15, and 20 days postinoculation. Chickens exhibited mild respiratory signs and depression. Viral RNA was detected in the kidney, lung and tracheas on days 1 to 13 PI, in the oviduct between, days 3 and 13, in testes between days 1 and 11 PI, and in the caecal tonsil consistently up to day 20 PI. The most remarkable clinical signs and virus detection appeared on day 1 PI. Data indicated that the number of infected chickens and viral RNA detection from tissues was reduced with increasing antibody titer on day 20 PI. The results demonstrated that the IRFIBV32 virus has wide tissue distribution for respiratory, urogenital, and digestive systems.

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Citations

May 31, 2013·Journal of the South African Veterinary Association·Peyman BijanzadSeyed A Pourbakhsh
Mar 10, 2016·Advances in Virology·Faruku BandeYusuf Abba
Dec 6, 2016·Avian Pathology : Journal of the W.V.P.A·Christopher BallKannan Ganapathy
Aug 5, 2017·Animal Health Research Reviews·Faruku BandeVenugopal Nair
Sep 30, 2020·Pathogens·Shahnas M NajimudeenMohamed Faizal Abdul-Careem
Sep 28, 2020·Microbial Pathogenesis·B ManswrK Ganapathy
Apr 24, 2021·Research in Veterinary Science·Basim ManswrKannan Ganapathy

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay
ELISA
PCR

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