PMID: 8581858Nov 1, 1995Paper

Pathogenesis of intrauterine infections with bovine viral diarrhea virus

The Veterinary Clinics of North America. Food Animal Practice
V Moennig, B Liess

Abstract

BVDV shares with other Pestiviruses the ability to cross the placenta of pregnant host animals. The effects of fetal infections are complex and depend on a number of factors, e.g., age of the zygote/embryo stage, no infection seems to occur. During the last one third of gestation the infection is terminated by the ontogeny of the fetal immune system. This leaves a window of susceptibility during early stages of fetal development allowing establishment of viral persistence and/or the development of a number of fetopathologic effects. Additionally, fertility problems and abortions are observed. Calves that are born immunotolerant to BVDV and persistently viremic display a wide variety of abnormalities. However, there is an unknown proportion of calves born without any clinical signs indicative of persistent infection. The time of fetal infection during the first stages of pregnancy seems to play a crucial role with respect to the lesions induced. Generally, early infections seem to induce less damage compared with late infections, suggesting an indirect, possibly immune-mediated pathogenesis. Additionally, direct virus-cell interactions may play a role. Few data exist about the influence of differences in viral virulence on fetal...Continue Reading

Citations

May 7, 2002·Journal of the American Veterinary Medical Association·Robert J CallanElizabeth S Williams
Mar 29, 2003·American Journal of Veterinary Research·Claudia A Muñoz-ZanziWesley O Johnson
Nov 25, 2003·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M StokstadT Løken
Mar 16, 2005·New Zealand Veterinary Journal·G Thobokwe, C Heuer
Oct 28, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Caroline da Silva SilveiraFederico Giannitti
Jul 8, 2011·Transboundary and Emerging Diseases·H AliA Cepica
Dec 17, 2016·The Journal of Veterinary Medical Science·Kaori TokudomeYasuo Moritomo
May 12, 1998·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D L GroomsL A Ward
May 12, 1998·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D L GroomsL A Ward
Jul 25, 2006·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·V L QuadrosE F Flores
Jan 13, 2018·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Lalitha PeddireddiIvan Leyva-Baca
Sep 11, 2001·Journal of the American Veterinary Medical Association·D L GroomsJ C Baker
Dec 18, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M Stokstad, T Løken
Apr 3, 2003·The Veterinary Quarterly·A L E Lindberg
Mar 26, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M BeerO R Kaaden
Nov 11, 2014·Annual Review of Animal Biosciences·Matthias Schweizer, Ernst Peterhans
Oct 5, 2011·Irish Veterinary Journal·Damien J BarrettH Michael Gunn
Nov 17, 2020·The Journal of Veterinary Medical Science·Kentaro HironakaYasuo Moritomo
Oct 27, 2001·Preventive Veterinary Medicine·L AlbanU Strøger

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