Pathogenesis of Mycoplasma pneumoniae: An update

Indian Journal of Medical Microbiology
Rama ChaudhryA Chandolia

Abstract

Genus Mycoplasma, belonging to the class Mollicutes, encompasses unique lifeforms comprising of a small genome of 8,00,000 base pairs and the inability to produce a cell wall under any circumstances. Mycoplasma pneumoniae is the most common pathogenic species infecting humans. It is an atypical respiratory bacteria causing community acquired pneumonia (CAP) in children and adults of all ages. Although atypical pneumonia caused by M. pneumoniae can be managed in outpatient settings, complications affecting multiple organ systems can lead to hospitalization in vulnerable population. M. pneumoniae infection has also been associated with chronic lung disease and bronchial asthma. With the advent of molecular methods of diagnosis and genetic, immunological and ultrastructural assays that study infectious disease pathogenesis at subcellular level, newer virulence factors of M. pneumoniae have been recognized by researchers. Structure of the attachment organelle of the organism, that mediates the crucial initial step of cytadherence to respiratory tract epithelium through complex interaction between different adhesins and accessory adhesion proteins, has been decoded. Several subsequent virulence mechanisms like intracellular localiza...Continue Reading

References

Jan 1, 1976·Journal of Bacteriology·M H Wilson, A M Collier
Feb 1, 1975·The American Journal of Medicine·H W MurrayR B Roberts
Nov 1, 1979·Acta paediatrica Scandinavica·J Y MokH Simpson
Aug 1, 1990·Infection and Immunity·C J SuJ B Baseman
Oct 1, 1986·Acta Neurologica Scandinavica·P O BehanI T Draper
Mar 1, 1973·The Journal of Infectious Diseases·W A Clyde
Jul 28, 1967·Annals of the New York Academy of Sciences·G Cohen, N L Somerson
Aug 1, 1982·The Journal of Infectious Diseases·M Kleemola, H Käyhty
Mar 1, 1995·The Pediatric Infectious Disease Journal·M NaritaT Togashi
Aug 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·H M Foy
Aug 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M Koskiniemi
Apr 1, 1996·Molecular Microbiology·D C Krause
Nov 15, 1996·Nucleic Acids Research·R HimmelreichR Herrmann
Jun 6, 2000·Acta Haematologica·E Bar MeirY Shoenfeld
Sep 1, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D BencinaM Narat
Feb 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M SocanJ Jazbec
Apr 11, 2001·The Journal of Allergy and Clinical Immunology·R J MartinG H Cassell
May 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A BitnunS Richardson
Aug 3, 2001·Pediatric Neurology·L A BruchW Squier
Apr 30, 2002·Current Opinion in Infectious Diseases·M R Hammerschlag
Jul 26, 2003·Seminars in Pediatric Infectious Diseases·Ari BitnunSusan Richardson
Jan 1, 1965·Acta Pathologica Et Microbiologica Scandinavica·G BIBERFELDJ JONSSON
Oct 19, 2004·Clinical Microbiology Reviews·Ken B Waites, Deborah F Talkington
Apr 21, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Yun-Fong NgeowYuet-Meng Cheong
Sep 24, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Takashi ShimizuKoichi Kuwano
Oct 29, 2005·American Journal of Respiratory and Critical Care Medicine·Judy M Hickman-DavisSadis Matalon
Nov 1, 1974·Infection and Immunity·M G GabridgeA M Cameron
Apr 18, 2006·Proceedings of the National Academy of Sciences of the United States of America·T R Kannan, Joel B Baseman
Nov 28, 2006·Frontiers in Bioscience : a Journal and Virtual Library·Rama ChaudhryPawan Malhotra
Dec 13, 2006·Pediatric Dermatology·Peter C SchalockJodi K Wenger
Mar 30, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S SinhaS Pradhan

❮ Previous
Next ❯

Citations

Mar 1, 2018·Physiological Reviews·A P HakanssonD Bogaert
Sep 11, 2019·Journal of Cutaneous Medicine and Surgery·Heidi Oi-Yee LiMichele L Ramien
Aug 22, 2020·Journal of Chemotherapy·Md Moinuddin SheamSudhangshu Kumar Biswas
Mar 23, 2020·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Fang TianShuang Li
Sep 30, 2017·FEMS Microbiology Reviews·Cedric Blötz, Jörg Stülke
Dec 6, 2018·Frontiers in Microbiology·Renato D'AlonzoSusanna Esposito
Jan 15, 2018·Allergologia et immunopathologia·M NaghibA Kariminik
Feb 6, 2021·Expert Opinion on Pharmacotherapy·Susanna EspositoNicola Principi
Jan 29, 2021·Pathogens·Zhulin JiangPolly H M Leung
Mar 19, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Guanhua XueJing Yuan
Mar 17, 2021·Journal of Clinical Laboratory Analysis·Fanjun MengLixin Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Protein Structures

Bacterial protein structures can expedite the development of novel antibiotics. Here is the latest research on bacterial proteins and the resolution of their structures.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Protein Structures (ASM)

Bacterial protein structures can expedite the development of novel antibiotics. Here is the latest research on bacterial proteins and the resolution of their structures.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Cytokine & Growth Factor Reviews
Jun YangDeborah F Talkington
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Pamela R WoodEdward G Brooks
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
Karina Jahnz-RózykBeata Zielnik-Jurkiewicz
© 2022 Meta ULC. All rights reserved