PMID: 11901463Mar 20, 2002Paper

Pathogenesis of the gradually elongated nerve

Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand
K IkedaS Tanaka

Abstract

The rabbits' sciatic nerves were lengthened by 30 mm in increments of 2.0 mm/day (2-mm group) and 4.0 mm/day (4-mm group). In the 2-mm group, the phosphorylated neurofilament (p-NF) immunoreactivity of axons was similar to that of the control group. However, in the 4-mm group, number of p-NF positive axons decreased. The number of p-NF positive cells at the seventh lumbar dorsal root ganglion cells of the 4-mm group was significantly larger than that of the control group. Abnormal p-NF immunoreactivity in the 4-mm group suggested an impairment of the axonal flow. Leakage of Evans blue-albumin into the endoneurial space, which meant destruction of the blood-nerve barrier function, was clearly evident in the 4-mm group, but minor in the 2-mm group. A speed of 2.0 mm/day, therefore, appears to be critical for safe nerve elongation in this model.

References

Jan 1, 1990·The Journal of Bone and Joint Surgery. British Volume·G GalardiA Paronzini
May 1, 1987·Journal of Neuropathology and Experimental Neurology·J RosenfeldD L Price
Mar 1, 1987·Journal of Pediatric Orthopedics·G De BastianiG Trivella
Aug 1, 1984·The Journal of Cell Biology·P N HoffmanD L Price
Oct 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·L A Sternberger, N H Sternberger
Mar 1, 1993·The Journal of Trauma·G D HallM Compton-Allen
Jun 1, 1996·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·M TanoueK Takagi
Nov 23, 2000·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·K IkedaS Tanaka

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Citations

Aug 18, 2005·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·K I Kazuo IkedaS T Shigenori Tanaka
Nov 25, 2005·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Norio HagiwaraShigeru Yokoyama
Jul 2, 2011·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Norie KoderaHiromoto Ito
Oct 21, 2016·Muscle & Nerve·Karina KouzakiKoichi Nakazato

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