PMID: 6729337Mar 1, 1984

Pathogenicity of anaerobic gram-negative rods: possible mechanisms

Reviews of Infectious Diseases
T Hofstad

Abstract

The literature dealing with the pathogenicity of anaerobic gram-negative rods in humans is reviewed. Knowledge concerning definite pathogenic mechanisms is, at best, cursory. There is evidence that encapsulation plays a role in the pathogenicity of Bacteroides fragilis and some of the black-pigmented Bacteroides. A range of enzymes, among them collagenase and IgA protease, are produced by several Bacteroides species. Supernatants of Fusobacterium necrophorum cultures may be leukotoxic. Synergism between anaerobic gram-negative rods and other bacterial species has been demonstrated in experimental animals.

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Related Concepts

Agglutination
Bacteroides
Cell Wall
Macrophage Chemotactic Factors
Antibiotic Resistance, Microbial
Endotoxins
Erythrocytes
Genus Fusobacterium
Phagocytosis
Polysaccharides, Bacterial

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