PMID: 6141205Nov 1, 1983

Pathogenicity of encapsulated Bacteroides melaninogenicus group, B. oralis and B. ruminicola subsp. brevis in abscesses in mice

The Journal of Infection
I BrookR I Walker

Abstract

The pathogenicity of 27 clinical isolates of the Bacteroides melaninogenicus (BM) group and four clinical isolates of B. oralis and B. ruminicola subsp. brevis were investigated by inoculating them into mice and subsequently determining their ability to cause subcutaneous (SC) or intraperitoneal abscesses. Only 11 isolates of BM group and one B. ruminicola induced abscesses in mice, and all were found to be heavily encapsulated on recovery from the abscesses (more than 50 per cent of the organisms were encapsulated). When the other 23 isolates, however, were injected SC in combination with either Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus or Streptococcus pyogenes, abscesses were formed in 16 of the 23 combinations. The Bacteroides spp. recovered from the mixed infection were heavily encapsulated. Capsules also formed in Bacteroides if the organisms were injected together with capsular material or formalin killed cells of K. pneumoniae or encapsulated Bacteroides sp. Once non-encapsulated or only slightly encapsulated strains acquired a capsule, they could induce abscesses on reinoculation into mice.

References

Nov 1, 1954·The Journal of Infectious Diseases·J B MACDONALDM L KNOLL

Citations

Jan 1, 1986·Antonie van Leeuwenhoek·I BrookR I Walker
Jan 1, 1987·Archives of Gynecology and Obstetrics·I Brook
Jun 1, 1984·European Journal of Clinical Microbiology·I BrookR I Walker
Jan 1, 1984·Antonie van Leeuwenhoek·D M MacLarenJ A Kaan
Jan 1, 1984·Antonie van Leeuwenhoek·T J van SteenbergenJ de Graaff
May 1, 1987·Veterinary Immunology and Immunopathology·D L Emery
Aug 1, 1990·Journal of Clinical Periodontology·G S BansalM Wilson
Dec 1, 1990·The British Journal of Oral & Maxillofacial Surgery·M A LewisD A McGowan
May 1, 1989·Journal of Periodontal Research·M E NeidersR J Genco
Apr 24, 2003·Pediatrics International : Official Journal of the Japan Pediatric Society·I Brook
Oct 9, 2004·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Panagiotis K Stefanopoulos, Alexandros E Kolokotronis
May 1, 1995·The Journal of Infection·I Brook, J D Gillmore
May 26, 2004·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Shuzo KanamoriAtsushi Saito
Jan 1, 1994·FEMS Microbiology Reviews·I Brook
Jan 1, 1987·Critical Reviews in Microbiology·I Brook

Related Concepts

Abscess
Metazoa
Bacteroides
Prevotella melaninogenica
Haemophilus influenzae
Klebsiella rhinoscleromatis
Mouse, Swiss

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