Pathologic characteristics of exophytic renal masses

Journal of Endourology
Michael C LipkeChandru P Sundaram

Abstract

Pathologic grade is an important prognostic factor for renal-cell carcinoma (RCC). The objective of this study was to determine if there is any association of radiologic characteristics with pathologic grade and type of small renal tumors. We retrospectively reviewed the records of 500 patients who underwent extirpative renal surgery. Fifty-one patients met the inclusion criteria of solitary RCC <6 cm and adequate radiologic imaging available for review. The axial images with the largest area of tumor growing into the kidney were evaluated by a single radiologist to determine the percent of tumor that was exophytic. Nine patients had tumors that were >67% exophytic, and 42 patients had tumors <67% exophytic. There is a statistically significant difference in the mean Fuhrman grade for these 2 groups (1.78 v 2.25, P < 0.01). The distribution of histologic subtype was as follows: 34 patients with clear cell, 15 with papillary, and one each with chromophobe and unclassified tumors. Papillary RCC comprised 78% (7 of 9) of tumors that were >67% exophytic and 15% (3 of 20) that were <33% exophytic. The relative risk of a >67% exophytic tumor being papillary v nonpapillary is 4.1. Exophytic renal tumors are more likely to be of lower ...Continue Reading

References

Nov 20, 2003·Urology·David A DucheneKenneth S Koeneman
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Dec 19, 2003·The Urologic Clinics of North America·Nicolette K JanzenArie S Belldegrun
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Mar 4, 2006·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun

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Citations

Dec 4, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·K Clint Cary, Chandru P Sundaram
Jan 11, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Ryuji MatsumotoKatsuya Nonomura
Aug 2, 2008·Current Opinion in Urology·Jorge RiojaM Pilar Laguna
Nov 19, 2020·Journal of Clinical Medicine·Ching-Chia LiWen-Jeng Wu

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