PMID: 8372030Jul 1, 1993

Pathologic examination of placentas from singleton and twin pregnancies obtained after in vitro fertilization and embryo transfer

Pediatric Pathology
P GavriilF Leroy


A pathologic investigation was conducted on 100 placentas collected from pregnancies resulting from in vitro fertilization (IVF) and intrauterine embryo transfer (ET), including 70 singleton pregnancies, 20 twin pregnancies, and 10 multiple pregnancies complicated by the vanishing twin (VT) phenomenon (n = 5) or artificially reduced (n = 5). These results were compared with those for 70 spontaneous spontaneous singleton and 20 spontaneous twin pregnancies. In cases of singleton pregnancies, the incidence of abnormal placental shapes was significantly different (P < .025) in the IVF group compared to controls. A significant (P < .005) difference was also observed between these groups in terms of umbilical cord insertion. The mean distance between the cord insertion and the closest placental margin was significantly (P < .001) shorter among IVF singleton pregnancies (3.19 +/- 1.83 versus 4.62 +/- 2.23 cm). In cases of twin pregnancy, no difference was found between IVF and spontaneous pregnancy in the incidence of pregnancy complications and distribution of cord insertion. First-trimester bleeding was the only clinical sign of the disappearance of an embryo in multiple pregnancies complicated by the VT phenomenon and was not obse...Continue Reading


Oct 16, 2003·Placenta·I CetinP Antonazzo
Aug 1, 1994·The Australian & New Zealand Journal of Obstetrics & Gynaecology·H Williams, H Jeffery
Jun 15, 2007·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Owen T M ChanKurt Benirschke
Apr 22, 2005·Journal of Perinatal Medicine·Sriram C PerniRebecca N Baergen
May 19, 2012·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Jolly JoyInez Cooke
Jun 27, 2014·BioMed Research International·Sophie BrouilletPascale Hoffmann
Dec 24, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·L RuiterE Pajkrt
Jan 1, 2013·Reproductive Biomedicine Online·Eric JauniauxRon Maymon
Jan 5, 2011·The Journal of Steroid Biochemistry and Molecular Biology·J M RaunigA C Collier
May 2, 2009·The Journal of Steroid Biochemistry and Molecular Biology·A C CollierM A Ward
Jul 14, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·Junichi HasegawaTakashi Okai
Jun 10, 2011·The Journal of Obstetrics and Gynaecology Research·Junichi HasegawaTakashi Okai
May 14, 2011·The Journal of Obstetrics and Gynaecology Research·Junichi HasegawaTakashi Okai
Sep 28, 2010·Prenatal Diagnosis·Junichi HasegawaTakashi Okai
Oct 3, 2015·American Journal of Obstetrics and Gynecology·Corinne HubinontEric Jauniaux
Sep 18, 2014·The Journal of Obstetrics and Gynaecology Research·Junichi Hasegawa
Aug 16, 2016·Fertility and Sterility·Lisa A VroomanMarisa S Bartolomei
Sep 23, 2008·Fertility and Sterility·Barbara LukeMarcelle I Cedars
Aug 5, 2008·Fertility and Sterility·George DaskalakisAris Antsaklis
Feb 6, 2017·American Journal of Obstetrics and Gynecology·Eric JauniauxRon Maymon
Nov 15, 2017·Journal of Assisted Reproduction and Genetics·Atsushi YanaiharaTakumi Yanaihara
Aug 14, 2018·Current Opinion in Obstetrics & Gynecology·Yaakov MelcerEric Jauniaux
May 8, 2008·Current Opinion in Obstetrics & Gynecology·Kevin S Richter
Apr 11, 2018·Journal of Assisted Reproduction and Genetics·Lauren W SundheimerMargareta D Pisarska
Jun 25, 2020·Clinical Case Reports·Caiyun LiaoLaura Detti


Nov 1, 1978·The Journal of Pathology·C J Jones, H Fox
Jan 13, 1990·Lancet·R J WapnerL B McCullough
Jun 1, 1990·American Journal of Obstetrics and Gynecology·Kurt Benirschke
May 1, 1990·Journal of Pediatric Surgery·D S WagnerR W Novak
Nov 1, 1987·Human Reproduction·F PuissantF Leroy
Mar 1, 1986·American Journal of Obstetrics and Gynecology·R FrydmanJ Testart
Apr 1, 1986·American Journal of Obstetrics and Gynecology·M C AndrewsA A Acosta
Aug 15, 1968·American Journal of Obstetrics and Gynecology·J E McLennan
Jan 1, 1982·Acta geneticae medicae et gemellologiae·H J LandyD Keith
Mar 1, 1992·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A Sampson, L C de Crespigny
Oct 1, 1953·American Journal of Obstetrics and Gynecology·R TORPIN

Related Concepts

Entire Embryo
Blastocyst Transfer
Blastocyst Implantation, Natural
Umbilical Cord Structure
Multiple Pregnancy
Pregnancy Complications
Fertilization in Vitro

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