Pathologic Features of Colorectal Inflammatory Polyps in Miniature Dachshunds

Veterinary Pathology
E UchidaKazuyuki Uchida

Abstract

The histopathologic characteristics of colorectal inflammatory polyps that formed in Miniature Dachshunds were compared with those of other colorectal proliferative lesions, including adenomas and adenocarcinomas. Fifty-three colorectal polypoid lesions were histopathologically classified into inflammatory polyps (26 cases), adenoma (18 cases), and adenocarcinoma (9 cases). All 26 dogs that were diagnosed with inflammatory polyps were Miniature Dachshunds, indicating that colorectal inflammatory polyps exhibit a marked predilection for this breed. The inflammatory polyps had complex histopathologic features and were classified into 3 stages based on their epithelial composition. In early stage (stage 1), the polyps tended to exhibit a thickened mucosa containing hyperplastic goblet cells, dilated crypts filled with a large amount of mucus, and mild lymphocyte and macrophage infiltration. In later stages (stages 2 and 3), more severe neutrophil infiltration, interstitial mucus accumulation, granulation tissue, and occasional osteoid tissue were seen. Also, a few small foci of dysplastic epithelial cells were detected. The hyperplastic goblet cells, which were a major component of the epithelium of the inflammatory polyps, were p...Continue Reading

References

Mar 1, 1997·Journal of the American Animal Hospital Association·K D ValeriusS J Withrow
May 20, 1999·Veterinary Pathology·M F McEntee, K A Brenneman
Aug 30, 2001·Proceedings of the National Academy of Sciences of the United States of America·T BrabletzT Kirchner
Jul 20, 2002·Veterinary Pathology·M F McEnteeN Neilsen
Mar 1, 2003·Journal of Clinical Pathology·A DavenportR F T McMahon
May 23, 2006·The International Journal of Biochemistry & Cell Biology·Christos TsatsanisAndrew N Margioris
Jan 9, 2007·World Journal of Gastroenterology : WJG·Berit BaumMarion Hewicker-Trautwein
Jun 1, 2010·Experimental Biology and Medicine·Meng-Hsing WuShaw-Jenq Tsai
Sep 30, 2010·Veterinary Pathology·M Doré
Feb 2, 2011·Pathology, Research and Practice·Reyhan BayrakHacer Haltas
Sep 8, 2011·The Journal of Veterinary Medical Science·Aki OhmiHajime Tsujimoto
Nov 23, 2011·The Journal of Veterinary Medical Science·Atsushi TsukamotoHajime Tsujimoto
Nov 17, 2012·The Journal of Veterinary Medical Science·Hirotaka IgarashiHajime Tsujimoto
Dec 25, 2013·Laboratory Investigation; a Journal of Technical Methods and Pathology·Michael K DameD Kim Turgeon

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Citations

Jan 17, 2017·The Journal of Veterinary Medical Science·Nozomu YokoyamaMitsuyoshi Takiguchi
Mar 21, 2018·Journal of the American Animal Hospital Association·Akira MurakamiTakashi Mori
Aug 12, 2017·Journal of Toxicologic Pathology·James K ChambersKazuyuki Uchida
Sep 5, 2017·The Journal of Veterinary Medical Science·Hirotaka IgarashiHajime Tsujimoto
May 20, 2020·Journal of Toxicologic Pathology·Tsubasa SaitoHiroyuki Nakayama
Dec 18, 2020·The Journal of Veterinary Medical Science·Aki OhmiHajime Tsujimoto

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