Pathologic myopia and choroidal neovascularization

American Journal of Ophthalmology
M L Hotchkiss, S L Fine

Abstract

In 14 of 27 eyes with choroidal neovascular membranes associated with severe myopia, visual acuity deteriorated two or more lines on the Snellen chart. Twelve of the 27 eyes became legally blind. Final visual acuity may be related to the position of the neovascular membrane within the posterior pole. Four of the eight eyes with new vessels outside of the foveal avascular zone had follow-up visual acuities of 6/12 (20/40) or better. Only one of five eyes with new vessels extending to the edge of the avascular zone had a final visual acuity of 6/12 (20/40) or better. Three of 14 eyes with a neovascular membrane beneath the foveal avascular zone had visual acuities of 6/12 (20/40) or better. Neovascularization associated with severe myopia clearly jeopardizes central visual acuity. Laser photocoagulation therapy may be useful in treating neovascular membranes outside the foveal avascular zone or extending to the edge of the perifoveal capillary network. A larger prospective study is needed to determine the guidelines for and efficacy of such treatment for patients with severe myopia who develop choroidal neovascularization.

References

Mar 1, 1975·American Journal of Ophthalmology·R M Klein, B J Curtin
Jan 1, 1971·American Journal of Ophthalmology·B J Curtin, D B Karlin
Mar 1, 1967·American Journal of Ophthalmology·J D Gass

❮ Previous
Next ❯

Citations

Nov 12, 2013·Journal français d'ophtalmologie·B MathieuC Creuzot-Garcher
Dec 24, 1997·Survey of Ophthalmology·M A HochmanM A Zarbin
Jul 18, 2003·Ophthalmology·Takeshi YoshidaManabu Mochizuki
Aug 4, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kengo HayashiManabu Mochizuki
Jan 1, 1990·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S HayasakaT Setogawa
Sep 1, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ute E K SchnurrbuschSebastian Wolf
Apr 22, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ariko KojimaManabu Mochizuki
Apr 25, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Akio OishiNagahisa Yoshimura
Aug 1, 1983·Ophthalmology·G R HamptonA C Bird
Dec 1, 1984·Ophthalmology·M P AvilaC L Schepens
Mar 9, 2010·Ophthalmology·Kengo HayashiManabu Mochizuki
Jun 23, 2009·American Journal of Ophthalmology·Takamitsu FujiwaraRichard F Spaide
Nov 9, 2007·American Journal of Ophthalmology·Noriaki ShimadaManabu Mochizuki
Dec 26, 2006·American Journal of Ophthalmology·Gianni VirgiliUgo Menchini
Mar 13, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Anna C S TanAdrian Koh
Sep 10, 2011·Clinical & Experimental Ophthalmology·Danny S NgClement W Chan
Sep 6, 2005·American Journal of Ophthalmology·Ilse KrebsAlexandra Goll
Apr 5, 2002·American Journal of Ophthalmology·Nadine HamelinGisèle Soubrane
Apr 7, 2010·Vision Research·Richard A Stone, Tejvir S Khurana
Jul 31, 2001·American Journal of Ophthalmology·M IchibeH Abe
Nov 14, 2002·American Journal of Ophthalmology·Yasuo Tano
Jul 6, 2014·The British Journal of Ophthalmology·Tien Y WongAdnan Tufail
Jul 2, 2016·Drugs·Kelvin Yi Chong TeoChui Ming Gemmy Cheung
Dec 3, 2003·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ariko KojimaManabu Mochizuki
Mar 1, 2006·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Jong-Jer LeePei-Chang Wu
May 1, 2004·Current Opinion in Ophthalmology·Kyoko Ohno-Matsui, Takeshi Yoshida
Mar 1, 1994·Seminars in Ophthalmology·J C Lamkin, L J Singerman
Feb 5, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Khaled S Nabawi, Ashraf S Shaarawi
Nov 18, 2003·Artificial Organs·Eyal Margalit, Srinivas R Sadda
Oct 25, 2017·Asia-Pacific Journal of Ophthalmology·Paradee KunavisarutAniki Rothova
Oct 24, 2017·Asia-Pacific Journal of Ophthalmology·Danny S C NgKyoko Ohno-Matsui

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.