PMID: 26320478Sep 1, 2015Paper

Pathologic Risk Factors and Oncologic Outcomes in Early-stage Cervical Cancer Patients Treated by Radical Hysterectomy and Pelvic Lymphadenectomy at a Thai University Hospital: A 7 year Retrospective Review

Asian Pacific Journal of Cancer Prevention : APJCP
Irene RuengkhachornJutatip Srisombat

Abstract

To evaluate the rate of pathologic high-risk factors, intermediate-risk factors, and treatment outcomes in early-stage cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy (RHPL). Medical records of stage IA-IIA1 cervical cancer patients who underwent RHPL during the 2006 to 2012 time period and patient follow-up data until December 2013 were reviewed. Of 331 patients, 52 women (15.7%) had pathologic high-risk factors and 59 women (17.8%) had intermediate-risk factors without high-risk factors. All studied patients had an initial complete response. At median follow-up time of 40.9 months (range 1-103.3 months) and mean follow-up time of 43.3±25.3 months, 37 women had disease recurrence and 4 women had died of disease. The most common site of recurrence was the pelvis (64.8%). Five- year and 10-year disease free survival rates were 96.1% and 91.5%, respectively. Five-year and 10-year overall survival rates were 100% and 99.4%, respectively. Independent factors related to recurrence were pelvic node metastasis (odds ratio [OR], 2.670; 95%CI, 1.001-7.119), and >1/3 cervical stromal invasion (OR, 3.763; 95%CI, 1.483-9.549). The rates of pathologic high-risk and intermediate-risk factors should be cons...Continue Reading

References

Apr 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W A PetersD S Alberts
Feb 24, 2006·Gynecologic Oncology·Shing-Shun Nelson SiuTony Kwok-Hung Chung
Jun 8, 2007·Gynecologic Oncology·Fabio GhezziValentino Bergamini
Jun 21, 2007·The Journal of Obstetrics and Gynaecology Research·Jong-Min LeeChan-Yong Park
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hong-Bing CaiHan-Yin Hou
Apr 4, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Sergio PecorelliFranco Odicino
Sep 18, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Usanee ChatchotikawongChairat Leelaphatanadit
Dec 4, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Antonino DittoFrancesco Raspagliesi

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Citations

Sep 12, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Shuai LiuZhengrong Zhou

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