Pathological changes in the subsynovial connective tissue increase with self-reported carpal tunnel syndrome symptoms

Clinical Biomechanics
Jimmy TatPeter J Keir

Abstract

Fibrosis and thickening of the subysnovial connective tissue are the most common pathological findings in carpal tunnel syndrome. The relationship between subsynovial connective tissue characteristics and self-reported carpal tunnel syndrome symptoms was assessed. Symptoms were characterized using the Boston Carpal Tunnel Questionnaire and Katz hand diagram in twenty-two participants (11 with symptoms, 11 with no symptoms). Using ultrasound, the thickness of the subsynovial connective tissue was measured using a thickness ratio (subsynovial thickness/tendon thickness) and gliding function was assessed using a shear strain index ((Displacement(tendon)-Displacement(subsynovial))/Displacement(tendon)x 100). For gliding function, participants performed 10 repeated flexion-extension cycles of the middle finger at a rate of one cycle per second. Participants with symptoms had a 38.5% greater thickness ratio and 39.2% greater shear strain index compared to participants without symptoms (p<0.05). Ultrasound detected differences the SSCT in symptomatic group that was characterized by low self-reported symptom severity scores. This study found ultrasound useful for measuring structural and functional changes in the SSCT that could provid...Continue Reading

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Citations

Apr 25, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Chen ZhangWei Peng
Nov 25, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Makoto MotomiyaNorimasa Iwasaki
Dec 4, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Calvin T F Tse, Peter J Keir
Dec 24, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Michal ByraSameer Shah
May 8, 2020·Veterinary Medicine and Science·Verena J M M SchrierPeter C Amadio
Oct 25, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Amanda Farias ZunigaPeter J Keir
Nov 8, 2017·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·V J M M Festen-Schrier, P C Amadio
Mar 23, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Yu-Chi SuYung-Tsan Wu
Feb 1, 2020·Journal of the Neurological Sciences·Amanda Farias ZunigaPeter J Keir
Jul 31, 2021·Clinical Biomechanics·Mohammad Hosseini-FaridPeter C Amadio
Aug 16, 2021·Journal of Bodywork and Movement Therapies·Hélio Rafael SoaresPaulo de Carvalho
Aug 16, 2021·Journal of Bodywork and Movement Therapies·Hélio Rafael SoaresPaulo de Carvalho

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