Pathology of melanoma

Surgical Oncology Clinics of North America
David E Elder

Abstract

The pathology of melanoma is discussed in relation to surgical diagnosis and management. Pitfalls that may result in problems of clinicopathologic communication are emphasized. A compelling vision for the future is that all tumors will be characterized by their driving oncogenes, suppressor genes, and other genomic factors. The success of targeted therapy directed against individual oncogenes, despite its limitations, suggests that a repertoire of targeted agents will be developed that can be used against a variety of different tumors, depending on the results of genetic testing. Nevertheless, histopathologic diagnosis and surgical therapy will remain mainstays of management for melanoma.

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Citations

Feb 2, 2016·The Journal of Investigative Dermatology·Sen GuoChunying Li
Sep 6, 2017·Journal of Cell Science·Olivia SusantoRobert H Insall
Jul 12, 2019·Frontiers in Oncology·Gabriela Klein CoutoTiago Collares

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