PMID: 18723954Aug 30, 2008Paper

Pathology of pulmonary aspergillomas

Indian Journal of Pathology & Microbiology
Rajeev ShahShobhana P Pandit

Abstract

Aspergilloma refers to a fungal ball formed by saprophytic overgrowth of Aspergillus species and is seen secondary to cavitatory/cystic respiratory diseases. Paucity of clinical and pathological data of aspergilloma in India prompted us to analyze cases of aspergilloma over 15 years. The clinical features were recorded in all and correlated with detailed pathological examination. Aspergillomas were identified in 41 surgical excisions or at autopsy. There was male predominance; half the patients were in their fourth decade. Episodic hemoptysis was the commonest mode of presentation (85.4%). Forty aspergillomas were complex, occurring in cavitatory lesions (82.9%) or in bronchiectasis (14.6%). Simple aspergilloma was seen as an incidental finding in only one. Tuberculosis was the etiological factor in 31 patients, producing cavitatory or bronchiectatic lesions; other causes were chronic lung abscess and bronchiectasis (unrelated to tuberculosis). Surgical resections are endorsed in view of high risk of unpredictable, life-threatening hemoptysis.

Citations

Sep 10, 2010·Current Opinion in Infectious Diseases·Koichi IzumikawaShigeru Kohno
Feb 18, 2016·Respiratory Investigation·Koichi Izumikawa
Nov 3, 2012·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·J CardosoI Carvalho
Feb 7, 2012·Revue de pneumologie clinique·J L RakotosonH R Rajaona
Apr 21, 2009·Clinics in Chest Medicine·Brent P Riscili, Karen L Wood
Jan 1, 2011·Case Reports in Infectious Diseases·Ioannis KokkonouzisVasilios Skoufaras
Dec 13, 2012·Annals of the New York Academy of Sciences·Matthew Pendleton, David W Denning
Dec 5, 2013·Mycoses·K E SchweerO A Cornely
Oct 10, 2015·Mycoses·J BeardsleyJ N Day
May 25, 2013·Respiratory Medicine·Georgia TunnicliffeFelix Chua
Dec 12, 2020·Journal of Fungi·Pakpoom Phoompoung, Methee Chayakulkeeree

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