PMID: 3750740Jul 1, 1986Paper

Pathology of vitamin D deficiency in growing turkeys

Veterinary Pathology
O R HedstromR L Horst

Abstract

Turkey poults were fed a vitamin D-deficient diet and examined for clinical signs and structural changes of bone and parathyroid glands. Vitamin D-deficient poults developed ricketic changes during days 10 to 14. Control poults (deficient diet plus vitamin D) did not develop rickets. In deficient poults, lengths of proliferating-prehypertrophied zones of growth plates increased significantly in the proximal tibiotarsus but were only slightly elongated in the distal tibiotarsus. Unmineralized hypertrophic chondrocyte zones increased in length rapidly in conjunction with a decrease in the length of mineralized hypertrophic degenerative zones; this occurred more rapidly in proximal than in distal tibiotarsus. Other ricketic changes included decreases in bone ash, total femoral bone ash (calcium, phosphorus, magnesium), bone length, and body weight. Plasma alkaline phosphatase was increased, calcium was normal, and phosphorus was normal or elevated. Parathyroids were hyperplastic and had foci of degeneration. Vitamin D3 metabolites 25OHD3, 1,25(OH)2D3, and 24,25(OH)2D3 were rapidly depleted. Increase in bone ash Ca/P ratios in deficient poults suggests that phosphorus may be selectively released from ricketic bone. Low 25OHD3 and 1...Continue Reading

References

Oct 6, 1978·Science·S Christakos, A W Norman
Sep 1, 1979·Journal of Ultrastructure Research·A H RoufosseM J Glimcher
Sep 1, 1975·British Poultry Science·C C Whitehead, C Fisher
Mar 26, 1974·Biochemistry·J C Knutson, H F DeLuca
Aug 1, 1973·The Journal of Nutrition·H S YangJ Brenes
Jan 1, 1982·Comparative Biochemistry and Physiology. A, Comparative Physiology·J F Leatherland, M B Renfree
Jan 1, 1982·Annals of Nutrition & Metabolism·I R Dickson, E Kodicek
Jan 1, 1983·Annual Review of Biochemistry·H F DeLuca, H K Schnoes
Jan 1, 1984·Metabolic Bone Disease & Related Research·I M Shapiro, A Boyde
Oct 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·Z Bar-ShavitA J Kahn
Feb 16, 1984·The New England Journal of Medicine·P F Coccia
Mar 1, 1980·Clinics in Endocrinology and Metabolism·L G Raisz
Aug 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·E AbeT Suda
Jan 1, 1982·The Journal of Cell Biology·J D MaloneA J Kahn
Oct 1, 1980·Arthritis and Rheumatism·M Owen
Sep 1, 1981·British Medical Bulletin·L Wolpert
Jun 1, 1958·The Journal of Experimental Medicine·L F BELANGER, B B MIGICOVSKY
Oct 1, 1978·Avian Pathology : Journal of the W.V.P.A·C ItakuraM Takahashi
Jan 1, 1975·Avian Pathology : Journal of the W.V.P.A·D R Wise

❮ Previous
Next ❯

Citations

Jul 29, 2016·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Sarah J Woodhouse, Markus Rick

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Veterinary Internal Medicine
C RusbridgeA P Bjornson
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Ismet AslanNermin Baserer
© 2021 Meta ULC. All rights reserved