PMID: 9633270Jun 20, 1998Paper

Pathophysiology of heart failure update: the role of neurohumoral activation in the progression of heart failure

AACN Clinical Issues
D K Moser

Abstract

Understanding the pathophysiologic mechanisms responsible for producing heart failure is necessary before effective treatments can be developed that increase survival and improve quality of life. Recent advances in the treatment of heart failure can be traced directly to improved appreciation of the role of neurohumoral activation in the pathophysiology of heart failure. Initially adaptive, neurohumoral activation ultimately results in a series of overadjustments that actively participate in the progression of heart failure. In this article, the role of neurohumoral activation, ventricular remodeling, and various peripheral vascular abnormalities in the pathophysiology of heart failure are explored.

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Citations

Aug 3, 2004·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Sushma A Mengi, Naranjan S Dhalla
Sep 15, 2006·The Canadian Journal of Cardiology·Jarmila MachackovaNaranjan S Dhalla
Mar 10, 2001·Biological Research for Nursing·E J Corwin
May 28, 2020·Journal of the American Heart Association·Aditi NayakArshed A Quyyumi
Sep 23, 2011·Journal of Cellular Biochemistry·Helena M KaijaKatja S Porvari
Jul 21, 2000·The Journal of Cardiovascular Nursing·C Deaton

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