Pathophysiology of pressure changes during intrauterine transfusion

American Journal of Obstetrics and Gynecology
U NicoliniC H Rodeck

Abstract

Intraperitoneal and umbilical vein pressure readings were obtained during intrauterine transfusion in patients with Rh alloimmunization. In 15 nonacidotic fetuses, mean umbilical vein pressure before transfusion (4.5 mm Hg, SD = 2.3) increased by 4.6 mm Hg (delta umbilical vein pressure confidence intervals +2.8 to +6.4; p less than 0.0001) with transfusion. delta Umbilical vein pressure correlated positively with the increase in hematocrit level (r = 0.55; p less than 0.05) and negatively with gestational age (r = -0.58; p less than 0.05). Basal umbilical vein pressure was raised in the only acidotic fetus, whereas delta umbilical vein pressure was 0. Intraperitoneal pressure was recorded in 11 fetuses before and after transfusion, five of which were associated with fetal heart rate changes or preexisting ascites. Basal intraperitoneal pressure (2.5 mm Hg, confidence intervals 1.4 to 3.6) was significantly lower than basal umbilical vein pressure (confidence intervals, 3.2 to 5.8; p less than 0.02). In uncomplicated intraperitoneal transfusions, intraperitoneal pressure rose significantly (delta intraperitoneal pressure = +5.8; confidence intervals 2.9 to 8.8; p less than 0.005). In four transfusions associated with fetal brad...Continue Reading

References

Sep 1, 1976·British Journal of Obstetrics and Gynaecology·E G RobertsonW Walker
Jan 1, 1986·Fetal Therapy·K H NicolaidesW Clewell
Jul 1, 1988·Archives of Disease in Childhood·U NicoliniC H Rodeck
Apr 1, 1988·American Journal of Obstetrics and Gynecology·R L BerkowitzH H Bernstein
Jul 1, 1987·American Journal of Obstetrics and Gynecology·K H NicolaidesC H Rodeck
May 29, 1986·The New England Journal of Medicine·P A GrannumJ C Hobbins
Apr 1, 1981·American Journal of Obstetrics and Gynecology·F D FrigolettoN T Griscom

❮ Previous
Next ❯

Citations

Jul 1, 1996·Obstetrics and Gynecology·B Schumacher, K J Moise
Dec 7, 1991·Lancet·T KiserudL R Hellevik
Jul 15, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D V SurbekW Holzgreve
Mar 1, 1994·American Journal of Obstetrics and Gynecology·R WelchC H Rodeck
May 1, 1993·American Journal of Obstetrics and Gynecology·M C HaeuslerC H Rodeck
Oct 1, 1990·American Journal of Obstetrics and Gynecology·G RizzoS Campbell
Feb 7, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Corinne Hubinont, Yves Ville
Mar 1, 1991·Blood Reviews·Y Tannirandorn, C H Rodeck
Apr 1, 1990·Baillière's Clinical Haematology·Y Tannirandorn, C H Rodeck
Jan 1, 1992·British Journal of Obstetrics and Gynaecology·U NicoliniJ Beacham
Aug 13, 2003·Prenatal Diagnosis·D Mahieu-CaputoM Dommergues
Mar 1, 1991·British Journal of Obstetrics and Gynaecology·U NicoliniC H Rodeck
Oct 10, 2018·Case Reports in Obstetrics and Gynecology·Daisuke KatsuraMadoka Furuhashi
Mar 2, 1992·The Medical Journal of Australia·S E Meagher, N M Fisk

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.