PMID: 9554215Apr 29, 1998Paper

Pathophysiology of upper airway obstruction during sleep

Clinics in Chest Medicine
M S Badr

Abstract

Obstructive sleep apnea is a common medical disorder with significant adverse health consequences. The pathogenesis of pharyngeal obstruction during sleep, however, remains elusive. This article addresses the key mechanisms of upper airway (UA) obstruction including the role of transmural pressure, pharyngeal compliance, pharyngeal dilating muscle activity and non-neuromuscular factors. A proposed scheme of the pathophysiology of UA obstruction is outlined.

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Citations

Oct 21, 2006·Sleep & Breathing = Schlaf & Atmung·Gabriel Julià-SerdàPedro Cabrera-Navarro
Jul 4, 2012·Sleep & Breathing = Schlaf & Atmung·Leonardo HaddadMarcio Abrahão
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Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Leila Kheirandish-Gozal
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