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Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age

bioRxiv

Mar 6, 2015

Andrew Anand BrownRichard M Durbin

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Abstract

Statistical factor analysis methods have previously been used to remove noise components from high dimensional data prior to genetic association mapping, and in a guided fashion to summarise biologically relevant sources of variation. Here we show how the derived factors summarising pat...read more

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  • Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age

    bioRxiv

    Mar 6, 2015

    Andrew Anand BrownRichard M Durbin

    PMID: 990016154

    DOI: 10.1101/016154

    Abstract

    Statistical factor analysis methods have previously been used to remove noise components from high dimensional data prior to genetic association mapping, and in a guided fashion to summarise biologically relevant sources of variation. Here we show how the derived factors summarising pat...read more

    11
    1

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