Jan 1, 1976

Pathways of microbial metabolism of parathion

Applied and Environmental Microbiology
D M Munnecke, D P Hsieh

Abstract

A mixed bacterial culture, consisting of a minimum of nine isolates, was adapted to growth on technical parathion (PAR) as a sole carbon and energy source. The primary oxidative pathway for PAR metabolism involved an initial hydrolysis to yield diethylthiophosphoric acid and p-nitrophenol. A secondary oxidative pathway involved the oxidation of PAR to paraoxon and then hydrolysis to yield p-nitrophenol and diethylphosphoric acid. Under low oxgen conditions PAR was reduced via a third pathway to p-aminoparathion and subsequently hydrolyzed to p-aminophenol and diethylthiophosphoric acid. PAR hydrolase, an enzyme produced by an isolate from the mixed culture, rapidly hydrolyzed PAR and paraoxon (6.0 mumol/mg per min). This enzyme was inducible and stable at room temperature and retained 100% of its activity when heated for 55 C for 10 min.

  • References
  • Citations34

References

  • We're still populating references for this paper, please check back later.

Mentioned in this Paper

Metabolic Process, Cellular
Biochemical Pathway
4-nitrophenol
Oxidation
Isolate compound
Metabolic Pathway
Hydrolase
Phosphacol
Bioremediation
Microbial

About this Paper

Related Feeds

Bioremediation (ASM)

Bioremediation is the treatment and removal of harmful pollutants or contaminants through the use of microorganisms. Discover the latest research here.