Patient acceptance and issues of education of two durable insulin pen devices

Diabetes Technology & Therapeutics
T AsakuraKlaus H Jensen

Abstract

Insulin pen devices offer patients a more convenient, accurate, and discreet mode of insulin delivery than traditional syringes and vials. This open-label, randomized, comparative crossover study assessed patient preference for two reusable pens: NovoPen 4 (Novo Nordisk A/S, Copenhagen, Denmark) and OptiClik (Sanofi-Aventis, Bridgewater NJ). Thirty-five diabetes patients with no previous experience of pen devices (mean age 56.7 years; range 17-80 years; 57% male) used both pens to deliver a 10 unit saline dose into an injection cushion. Half received guidance according to official instruction manuals, and half were given no instructions. Learning times were also measured. Participants completed a detailed questionnaire to determine their preferences. Overall, 32 of 35 participants preferred NovoPen 4 compared with two of 35 for OptiClik (91.4% vs. 5.7% respectively, P<0.001), and one had no preference. NovoPen 4 was significantly favored over OptiClik in almost all questionnaire criteria, including safety (P<0.001), size of pen (P<0.001), appearance (P<0.001), and ease of use (P<0.001). The majority of patients were able to use NovoPen 4 without guidance (94.4%) compared with just over half for for OptiClik (55.6%, P<0.01). Lea...Continue Reading

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Citations

Oct 2, 2013·PharmacoEconomics·Susan M JoyJohn F P Bridges
Feb 5, 2011·Diabetes Technology & Therapeutics·Alfred Penfornis
Mar 22, 2012·Expert Opinion on Drug Delivery·Xiaohui GuoSøren Kruse Lilleøre
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Mar 1, 2012·Pharmaceutical Statistics·Haoda FuWilliam Huster
Oct 27, 2011·Journal of Diabetes Science and Technology·Arnd FriedrichsSteffen Adler
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Nov 30, 2016·Journal of Diabetes Science and Technology·David C KlonoffCatherine Domenger
Mar 4, 2021·Current Medical Research and Opinion·Debmalya Sanyal, Amarta Shankar Chowdhury

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