Patient and disease characteristics associated with late tumour stage at presentation of cervical cancer in northwestern Tanzania

BMC Women's Health
Ramadhani MlangeBenson R Kidenya

Abstract

About two thirds of patients with cervical cancer in Tanzania present with advanced tumor stage, leading to significant morbidity and mortality. We designed a study to determine the factors associated with the late tumour stage at presentation among patients with cervical cancer in Mwanza. This cross-sectional study recruited women at Bugando Medical Centre (BMC) with histologically confirmed cervical cancer from November 2013 to April 2014. Patients were recruited serially until the sample size was reached. A total of 202 women with histologically confirmed cervical cancer were recruited. The mean age of the patients was 50.5 ± 13.3 years. The majority of patients (n = 129, 63.9%) were diagnosed with late stage disease (IIB-IVB). Patients also presented with severe anemia (n = 78, 38.6%), urinary tract infections (n = 74, 36.6%), hydronephrosis (n = 43, 21.2%), elevated serum creatinine levels (n = 33, 16.3%), vesicovaginal fistula (VVF), (n = 13, 6.4%), lung metastasis (n = 5, 2.4%), metastasis to the urinary bladder (n = 4, 1.9%), rectovaginal fistula (RVF) (n = 3, 1.4%), liver metastasis (n = 2, 0.9%) and hydroureter (n = 2, 0.9%). In multivariate logistic regression, factors associated with late stage at presentation were ...Continue Reading

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Citations

Aug 18, 2017·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Tara J RickKari A Hartwig
Jan 15, 2021·BMJ Open·Tanimola MartinsWilliam Hamilton
Jul 17, 2019·Gynecologic Oncology Reports·Ava S RungeKrishnansu S Tewari
Jul 13, 2021·Cancer Cell International·Huilin ZhangBingjian Lu

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Methods Mentioned

BETA
hysterectomy
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