Patient and physician predictors of patient receipt of therapies recommended by a computerized decision support system when initially prescribed broad-spectrum antibiotics: a cohort study

Journal of the American Medical Informatics Association : JAMIA
Angela ChowOnyebuchi A Arah

Abstract

Antibiotic computerized decision support systems (CDSSs) were developed to guide antibiotic decisions, yet prescriptions of CDSS-recommended antibiotics have remained low. Our aim was to identify predictors of patients' receipt of empiric antibiotic therapies recommended by a CDSS when the prescribing physician had an initial preference for using broad-spectrum antibiotics. We conducted a prospective cohort study in a 1 500-bed tertiary-care hospital in Singapore. We included all patients admitted from October 1, 2011 through September 30, 2012, who were prescribed piperacillin-tazobactam or carbapenem for empiric therapy and auto-triggered to receive antibiotic recommendations by the in-house antibiotic CDSS. Relevant data on the patient, prescribing and attending physicians were collected via electronic linkages of medical records and administrative databases. To account for clustering, we used multilevel logistic regression models to explore factors associated with receipt of CDSS-recommended antibiotic therapy. One-quarter of the 1 886 patients received CDSS-recommended antibiotics. More patients treated for pneumonia (33.2%) than sepsis (12.1%) and urinary tract infections (7.1%) received CDSS-recommended antibiotic therap...Continue Reading

References

Jan 22, 1998·The New England Journal of Medicine·R S EvansJ P Burke
Apr 6, 2000·International Journal of Epidemiology·S Greenland
Mar 23, 2002·The Journal of Antimicrobial Chemotherapy·Erwin M Brown
Sep 26, 2002·Pharmacoepidemiology and Drug Safety·Roel FijnJacobus R B J Brouwers
Jun 7, 2005·American Journal of Respiratory and Critical Care Medicine·Rosario MenéndezUNKNOWN NEUMOFAIL Group
Jun 28, 2005·The Lancet Infectious Diseases·David M Livermore
Jan 18, 2006·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Karin A ThurskyGraham V Brown
Jan 25, 2006·European Journal of Clinical Pharmacology·Peter G M MolFlora M Haaijer-Ruskamp
Apr 20, 2006·Journal of the American Medical Informatics Association : JAMIA·Jessina C McGregorAnthony D Harris
Sep 5, 2006·International Journal of Medical Informatics·Karin A Thursky, Michael Mahemoff
Sep 26, 2006·The Journal of Antimicrobial Chemotherapy·Mical PaulUNKNOWN TREAT Study Group
Feb 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ronald E PolkConan MacDougall
Nov 4, 2008·Emerging Infectious Diseases·Nienke van de Sande-BruinsmaUNKNOWN European Surveillance of Antimicrobial Consumption Project Group
Nov 7, 2008·Current Opinion in Infectious Diseases·Vitali SintchenkoGwendolyn L Gilbert
Jan 13, 2010·Journal of the American Medical Informatics Association : JAMIA·Annette MoxeySallie-Anne Pearson
Aug 25, 2010·Antimicrobial Agents and Chemotherapy·Mical PaulLeonard Leibovici
Jan 13, 2011·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Christopher A Ohl, Vera P Luther
Feb 15, 2011·Infectious Disease Clinics of North America·Pranita D Tamma, Sara E Cosgrove
Mar 16, 2011·Scandinavian Journal of Infectious Diseases·Gustavo Hideki Kawanami, Carlos Magno Castelo Branco Fortaleza
Apr 25, 2012·Journal of Medical Systems·Kristof SteurbautFilip De Turck
Apr 11, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E CharaniA Holmes

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Related Papers

International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care
K A ThurskyG V Brown
International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care
Subhash C AryaShekhar Agarwal
Medical Decision Making : an International Journal of the Society for Medical Decision Making
Victoria A ShafferMitchell A Medow
© 2021 Meta ULC. All rights reserved