Patient and physician preferences for surgical and adjuvant treatment options for rectal cancer

Archives of Surgery
J D HarrisonStephen Clarke

Abstract

Patients and their clinicians hold varying preferences for surgical and adjuvant treatment therapies for rectal cancer. Preferences were determined using the Prospective Measure of Preference. Royal Prince Alfred and St Vincent's hospitals in Sydney, Australia. Patients with colorectal cancer were interviewed during their postoperative hospital stay, and physicians were asked to complete a mailed survey. The Prospective Measure of Preference method produces 2 outcome measures of preference: willingness to trade and prospective measure of preference time trade-off. Patients' strongest preference was to avoid a stoma: more than 60% would give up a mean of 34% of their life expectancy to avoid this surgical option. This was followed by treatment options involving chemoradiotherapy, where more than 50% would give up a mean of almost 25% of their life to avoid treatment. Surgeons held stronger preferences against all adjuvant options compared with oncologists (P </= .01). Patients had strong preferences against all treatment options, and these preferences frequently differed from those of physicians. These results highlight the importance of determining patients' own preferences in the clinical encounter. Furthermore, the diversity ...Continue Reading

Citations

Mar 27, 2013·Applied Health Economics and Health Policy·Axel C Mühlbacher, Christin Juhnke
Mar 18, 2011·World Journal of Gastroenterology : WJG·Jürgen Mulsow, Des C Winter
Sep 25, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Vanessa L BeesleyAdele C Green
Jun 26, 2013·Journal of Vascular and Interventional Radiology : JVIR·Govindarajan SrimathveeravalliStephen B Solomon
Jan 20, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Y RibasA D'Hoore
Jun 7, 2011·American Journal of Surgery·Jürgen J W MulsowSean Tierney
Feb 9, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Prunella BlinmanMartin Stockler
Dec 3, 2015·Clinical Oncology : a Journal of the Royal College of Radiologists·R Glynne-Jones, R Hughes
Aug 27, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A CurrieR Kennedy
Jan 17, 2012·The British Journal of Surgery·S T MartinD C Winter
Mar 21, 2012·Head & Neck·Drew C BrotherstonJames R Wright
Jan 1, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C M ByrneM J Solomon
Oct 22, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A H W SchiphorstM E Hamaker
Apr 26, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K BujkoM Spalek
Aug 8, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Shelagh M SzaboJorge Cortes
Jul 13, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D PapamichaelM Aapro
Jan 23, 2009·Patient Education and Counseling·James D HarrisonTim Whelan
May 19, 2018·American Journal of Men's Health·Masahiko NakayamaJörg Mahlich
Oct 13, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·James D HarrisonJonathan Carter
Jun 28, 2019·JAMA Oncology·Fahima DossaNancy N Baxter
Jan 25, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Fahima DossaNancy N Baxter
Feb 10, 2011·Diseases of the Colon and Rectum·Mikaela L JorgensenMichael J Solomon
Mar 10, 2016·Diseases of the Colon and Rectum·Michael J Solomon
Oct 27, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Louisa G GordonPenelope M Webb
Sep 29, 2018·BJS Open·A L YoungG J Toogood
Feb 3, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·T KoëterJ H W de Wilt

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