Patient and Public Preferences for Treatment Attributes in Parkinson's Disease

The Patient
Marieke G M WeerninkMaarten J IJzerman

Abstract

Patient and public preferences for therapeutic outcomes or medical technologies are often elicited, and discordance between the two is frequently reported. Our main objective was to compare patient and public preferences for treatment attributes in Parkinson's disease (PD). A representative sample from Dutch PD patients and the general public were invited to complete a best-worst scaling case 2 experiment consisting of six health-related outcomes and one attribute describing the specific treatment (brain surgery, pump, oral medication). Data were analyzed using mixed logit models, and attribute impact was estimated and compared between populations (and population subgroups). Both the public (N = 276) and patient (N = 198) populations considered treatment modality the most important attribute, although patients assigned higher relative importance. Both groups assigned high disutility to pump infusion and brain surgery and preferred drug treatment. Most health outcomes were valued equally by patients and the public, with the exception of reducing dizziness (more important to the public) and improving slow movement (more important to patients). Although these data do not support definite conclusions on whether patients are less li...Continue Reading

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