Patient attitudes regarding participation in studies of antimicrobial resistance

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Pam TolomeoEbbing Lautenbach

Abstract

A number of recent studies of antimicrobial resistance have focused on the role of antimicrobial-resistant pathogens that colonize the gastrointestinal tract. However, participation rates have been low in studies that involve fecal sampling. Attitudes toward such studies among potential study participants have not been assessed. We conducted a cross-sectional survey, enrolling 3 groups of inpatients from a large academic center. Group 1 consisted of patients who had previously participated in a cohort study of fluoroquinolone-resistant Escherichia coli, which involved the collection of perirectal swab samples. Group 2 consisted of patients who had previously refused to participate in the study of fluoroquinolone-resistant E. coli. Group 3 consisted of patients who had never been asked to participate in the study of the fluoroquinolone-resistant E. coli. The survey assessed patients' attitudes and beliefs regarding medical research and their willingness to consent to collection of a perirectal swab sample. Response options were recorded on a 5-point Likert scale. The Fisher exact test was used to compare dichotomized responses across study groups. A total of 90 patients were surveyed: there were 29 in group 1 and in group 2 and ...Continue Reading

References

Nov 20, 2002·Archives of Internal Medicine·Giselle Corbie-SmithDiane Marie M St George
Oct 4, 2003·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Ilene WiletsDenise Nassisi
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Curtis J Donskey

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