Patient attitudes towards brain donation across both neurodegenerative and non-neurodegenerative neurological disorders

Cell and Tissue Banking
Reudi J W ChanAdeline S L Ng

Abstract

Brain donations are imperative for research; understanding possible barriers to entry is required to improve brain donation rates. While a few surveys have studied attitudes towards brain banking in patients with neurodegenerative disorders, none have surveyed patients with chronic neurological disorders but without neurodegeneration. This cross-sectional study was conducted on 187 participants, with both neurodegenerative (n = 122) and non-neurodegenerative disorders (n = 65), to compare their attitudes and preferences towards brain donation. Encouragingly, patients with non-neurodegenerative disorders were just as likely to consider brain donation as those with neurodegenerative diseases. Approximately half of each group were willing to consider brain donation, and majority of participants across both groups would not be offended if asked to participate in brain donation (71%). Across both groups, altruistic reasons such as desire to advance medical knowledge and benefit to other patients were the main motivating factors for brain donation, while perceived stress for family members, fears of body disfigurement and religious reasons were the main reasons against brain donation. Of note, nearly two-thirds of all participants we...Continue Reading

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Citations

Jun 23, 2020·Journal of Alzheimer's Disease : JAD·Aldelmo Emmanuel Reyes-PabloJosé Luna-Muñoz
Jan 14, 2021·Journal of Neural Transmission·Cara Fernandez-CeradoGeraldine Acuña-Sunshine

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