Patient awareness about family planning represents a major knowledge gap in multiple sclerosis

Multiple Sclerosis and Related Disorders
Peter Vestergaard RasmussenKlaus Gregaard Madsen

Abstract

The purpose of the survey was to assess the knowledge of family planning issues associated with disease modifying therapies (DMTs) among patients diagnosed with multiple sclerosis (MS). 590 Danish MS patients responded to an online questionnaire about family planning in MS, collecting demographics, disease characteristics, disease modifying treatment, knowledge of potential teratogenic effects in DMTs, number of children, occurrence of unplanned pregnancies and outcome, and sources of information. 488 females and 102 males, mean age 40 years, responded. On average, it was 6.5 and 10.9 years since diagnosis and first symptoms, respectively. 16% of female and 19% of male respondents did not receive DMT at the time of responding to the survey. 30% of all had received only one DMT, 37%, 19%, 8%, and 5% had received two, three, four, and five different treatments, respectively. 42% of female and 74% of male respondents said they did not know if the medication they were taking had teratogenic risks. 83% of females and 85% of males responded that they did not know, whether DMT in male MS patients may expose healthy partners to teratogenic risks; hereto, 13% and 10%, respectively, answered that no transmission occurs. On average respon...Continue Reading

Citations

Jun 11, 2020·Expert Opinion on Pharmacotherapy·Johanna B Andersen, Melinda Magyari
Aug 9, 2019·Journal of Medical Internet Research·Bita RezaallahBritt-Isabelle Berg
Dec 20, 2019·Multiple Sclerosis Journal - Experimental, Translational and Clinical·Andrew L SmithMary Rensel
Sep 26, 2020·Multiple Sclerosis and Related Disorders·Ramón Villaverde-GonzálezÁngel Pérez Sempere
May 18, 2021·Frontiers in Neurology·Simona BonavitaDominic Jack
Jul 3, 2021·Multiple Sclerosis Journal - Experimental, Translational and Clinical·Ricardo AlonsoNora Fernández Liguori

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