Patient burden and quality of life in atopic dermatitis in US adults: A population-based cross-sectional study

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Jonathan I SilverbergZelma C Chiesa Fuxench

Abstract

The patient burden and quality of life (QOL) impact of atopic dermatitis (AD) in the United States population is not well established. To elucidate the patient burden of AD in the US population. A cross-sectional, population-based study of 602 adults was performed. Atopic dermatitis was determined using modified UK Diagnostic Criteria for AD. Its severity was assessed using self-reported global AD severity, Patient-Oriented Eczema Measure (POEM), Patient-Oriented Scoring AD (PO-SCORAD), PO-SCORAD-itch, and sleep. Quality of life was assessed using short-form (SF-)12 mental and physical health scores and Dermatology Life Quality Index (DLQI). Adults with AD reported higher proportions of having only fair/poor overall health (25.8% vs. 15.8%), being somewhat/very dissatisfied with life (16.7% vs 11.4%), lower weighted mean (standard deviation [SD]) SF-12 mental (45.9 [9.9] vs 50.9 [9.2]) and physical health subscores (53.0 [2.5] vs 53.5 [2.3]) and higher DLQI (4.9 [6.5] vs 1.1 [2.8]). In multivariable regression models adjusting for sociodemographics and multiple comorbid health disorders, significant stepwise decreases by AD severity (self-reported, POEM, PO-SCORAD) of overall health, life satisfaction, SF-12 mental health, and ...Continue Reading

Citations

Sep 25, 2018·The British Journal of Dermatology·K R PatelJ I Silverberg
Mar 7, 2019·The British Journal of Dermatology·J I SilverbergE L Simpson
Mar 19, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·J I SilverbergJ M Gelfand
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Jan 14, 2020·International Journal of Dermatology·Gurkiran BirdiRebecca C Knibb
Feb 13, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Costner McKenzie, Jonathan I Silverberg
Sep 17, 2019·Dermatitis : Contact, Atopic, Occupational, Drug·Partik Singh, Jonathan Silverberg
Mar 17, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·J P ThyssenA Egeberg
Apr 30, 2020·The British Journal of Dermatology·J I SilverbergDerek Y Hsu
Sep 26, 2020·Dermatology and Therapy·Ken-Ichi YasudaAkihiko Asahina
Mar 27, 2020·Expert Opinion on Pharmacotherapy·Jocelyn T MendesSteven R Feldman
May 30, 2019·American Journal of Clinical Dermatology·Paras P Vakharia, Jonathan I Silverberg
May 18, 2019·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Ariel MitevValentin Brodszky
May 15, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Silvia CapucciNana Kragh
Sep 19, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Donald K LeiJonathan I Silverberg
Mar 14, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Costner McKenzie, Jonathan I Silverberg
Oct 8, 2020·The Journal of Dermatological Treatment·Marco BoeriMarco Di Bonaventura
May 3, 2020·International Journal of Environmental Research and Public Health·Pier A SpinazzeNiels H Chavannes
Oct 28, 2020·Archives of Dermatological Research·Sherief R JanmohamedJonathan I Silverberg
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Jan 10, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jonathan I SilverbergLaurent Eckert
Dec 23, 2020·Photodermatology, Photoimmunology & Photomedicine·Ilan VashurinShoshana Greenberger
Nov 24, 2019·The Medical Clinics of North America·Jonathan I Silverberg
Dec 18, 2020·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jonathan I SilverbergAndreas Wollenberg
Oct 6, 2018·Journal of the American Academy of Dermatology·Shanthi Narla, Jonathan I Silverberg
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Oct 27, 2018·Journal of the American Academy of Dermatology·Kevin R PatelJonathan I Silverberg
Nov 17, 2020·Archives of Dermatological Research·Tammy HuaJonathan I Silverberg

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