Patient, Caregiver, and Nurse Preferences for Treatments for Bone Metastases from Solid Tumors

The Patient
Yi QianCynthia Campbell-Baird

Abstract

Bone-targeted agents (BTAs) used for the prevention of skeletal-related events (SREs) associated with metastatic bone disease possess different attributes that factor into treatment decisions. The aim of this study was to evaluate preferences of patients, caregivers, and nurses for features of BTAs used to prevent SREs in patients with a self-reported physician diagnosis of bone metastasis from solid tumors. Patients (n = 187), primary caregivers (n = 197), or nurses (n = 196) completed a web-enabled discrete-choice experiment (10-question survey) in which they chose between pairs of hypothetical profiles of BTAs. Each profile was defined by six key treatment attributes, including efficacy and safety (two each) and route/frequency of administration and cost (one each). The relative importance of treatment attributes and levels was estimated. The most important treatment attribute for patients and nurses was out-of-pocket cost, and for caregivers, treatment-related risk of renal impairment. Risk of renal impairment was the second most important attribute for patients and nurses, while time until first SRE was the third most important attribute for all respondents. For nurses, risk of osteonecrosis of the jaw was least important,...Continue Reading

References

Oct 14, 2003·The Lancet Oncology·Jessica Corner
Feb 14, 2004·BMJ : British Medical Journal·Mandy Ryan
Oct 2, 2004·The Oncologist·Robert E Coleman
Oct 8, 2004·The New England Journal of Medicine·Ian F TannockUNKNOWN TAX 327 Investigators
Mar 1, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K P WeinfurtK A Schulman
Feb 16, 2006·Clinical Oncology : a Journal of the Royal College of Radiologists·E ChowG Velikova
Oct 26, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Robert E Coleman
Aug 30, 2008·Alzheimer Disease and Associated Disorders·A Brett HauberRaymond J Townsend
May 26, 2009·Journal of Health Economics·Semra OzdemirA Brett Hauber
Nov 27, 2009·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Corey Langer, Vera Hirsh
Mar 11, 2010·Health Economics·F Reed JohnsonKathryn A Phillips
Jun 29, 2010·International Journal of Clinical Practice·M Emberton
Nov 10, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alison T StopeckAda Braun
Jun 15, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·John F P BridgesJosephine Mauskopf
Aug 23, 2011·PharmacoEconomics·Ateesha F MohamedMaureen P Neary
Mar 1, 2012·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·John F P BridgesA Brett Hauber
Sep 15, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Allan LiptonSusie Jun
Jan 23, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·F Reed JohnsonJohn F P Bridges
Jan 25, 2013·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Justin J CoranChrista L Arnold
Mar 23, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kaitlin KooEdward Chow
Mar 27, 2013·Applied Health Economics and Health Policy·Axel C Mühlbacher, Christin Juhnke
Aug 27, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Roger von MoosKaren Chung
Sep 4, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·May HagiwaraKaren Chung
Jan 31, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Debu TripathyJudd W Moul
Jun 19, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Guy HechmatiJean-Jacques Body
Jun 28, 2014·Oncology Nursing Forum·Joseph D TarimanDonna L Berry
Aug 19, 2014·The Prostate·A Brett HauberJean-Jacques Body
Jan 18, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Jorge ArellanoYi Qian

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