Patient characteristics and clinical outcomes in a specialised intestinal failure unit: An observational cohort study.

Clinical Nutrition ESPEN
Marcel Kjærsgaard EriksenChristian Lodberg Hvas

Abstract

Intestinal failure (IF) is defined by a need for intravenous (IV) supplementation. Patients may present with multiple morbidities, and IV treatments carry a risk for catheter-related complications. Few studies described patient characteristics and clinical outcomes according to type of IF. We consecutively included patients who were admitted to a newly established inpatient IF unit (IFU) from 2013 through 2017. We evaluated patient characteristics and clinical outcomes of all patients' first admission. Outcomes included IF classification, length of stay, central line-associated blood stream infection (CLABSI), and discharge on home parenteral support (HPS). Follow-up was conducted six months after discharge for mortality and the continued need for HPS. A total of 236 patients were evaluated, including 39 (17%) with type 1 IF, 123 (52%) with type 2 IF, and 74 (31%) with type 3 IF. Of 91 who had a central venous catheter (CVC) on admission, CLABSI was present in 11 (12%). The CLABSI occurrence during admission was 2 (1%) of 173 patients with a CVC. Mean length of stay declined from mean 33 days (95% confidence interval (CI): 26.2-42.5) in 2013 to 15 days (95% CI: 12.2-17.7) in 2017 (p < 0.0001). Undiagnosed comorbidity was reveal...Continue Reading

Citations

Aug 26, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Marcel Kjaersgaard EriksenChristian Lodberg Hvas
Jul 19, 2021·Alimentary Pharmacology & Therapeutics·Marcel Kjaersgaard EriksenChristian Lodberg Hvas
Jul 23, 2021·JPEN. Journal of Parenteral and Enteral Nutrition·Hamed NikoupourSaman Nikeghbalian
Feb 10, 2021·European Journal of Gastroenterology & Hepatology·Anne K PohjuTaina M Sipponen

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